超广谱β内酰胺酶(ESBL)的临床特点及对策  

Clinical Characteristic and Countermeasure on Extended Spectrum β-Lactamase(ESBL)

作　　者：洪继平[1] 刘红星[1] 许冀陕[1] 

机构地区：[1]中日友好医院普内科药学部

出　　处：《当代医学》2000年第11期68-69,72,共3页Contemporary Medicine

摘　　要：本文介绍大肠杆菌及 克雷伯菌产生ESBLs对第三代头孢菌素耐药,而柠檬酸杆菌、沙雷茵、阴沟杆菌及绿脓杆菌产生Amp C酶对头孢一、二 三代抗生素耐药。产生ESBLs细菌对亚胺培南/西司他丁敏感,产生Amp C酶的细菌对亚胺培南/西司他丁第四代头孢菌素敏感。Ceph 3 were resistant to ESBLs producing by E.coli and Klebsella, ceph 1, ceph 3 were resistant to Amp C β lactamase producing by Citrobacter, Serratia Enterobacter cloacae and Pseudomonas aeruginosa. ESBL producing by bacterias were sensitlve to (Tienem) and Amp C βlactamase producing by bacterias were sensitive to imipenem/ cilastatin and ceph 4.

关 键 词：超广谱Β内酰胺酶 亚胺培南 西司他丁 ESBL 

分 类 号：R446.5[医药卫生—诊断学]