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作 者:杨璐[1] 赵文利[2] 李秋平[2] 许靖[2] 封志纯[2]
机构地区:[1]南方医科大学八一临床医学院,北京100700 [2]北京军区总医院新生儿科,100700
出 处:《重庆医学》2013年第28期3350-3352,共3页Chongqing medicine
基 金:国家自然科学基金资助项目(30973210;81070524)
摘 要:目的分析胎盘早剥新生儿的临床特点及凝血指标改变。方法收集2012年8月至2013年1月南方医科大学八一临床医学院新生儿监护病房胎盘早剥患儿60例为观察组,非胎盘早剥患儿60例作为对照组,进行两组临床及实验室指标分析。结果两组患儿比较观察指标,其中胎龄、多胎、胎膜早破、出生体质量、小于胎龄儿、母亲年龄、孕母妊娠期高血压、妊娠期糖尿病、新生儿窒息史、入院时活化部分凝血活酶时间(APTT)、D-二聚体(D-D),差异有统计学意义(P<0.05)。结论胎盘早剥系胎盘功能不全,新生儿继发凝血功能紊乱,呈病理性高凝状态。Objective To analyze the clinical characteristics and coagulation parameters of the infants with placental abruption. Methods Analysis was made on clinical and laboratory indexes of the hospitalized children of the NICU of Bayi Clinical Medical College of South Medical University,enrolled from August 2012 to January 2013,including 60 infants with placental abruption as observation group and 60 infants without placental abruption as the control group. Results From clinical manifestations and lab date, significant differences were found in gestational age, polyembryony, premature rupture of membrane, birth weight, intrauterine growth retardation, motherhood gestational hypertension, mother gestational diabetes mellitus, asphyxia, APTT, D-dimer on admis- sion between the observation group and control group(P〈0.05). Conclusion Placental abruption is the result of placental insuffi- ciency,which may cause coagulation disorder and thus show the pathological state of high condensation in infants.
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