长期不明原因发热388例临床分析  

Clinical analysis of 388 patients with long-term fever of unknown origin

作　　者：谢姣[1] 伏振[1] 刘旭[1] 梅丽[1] 李松明[1] 张继先[1] 

机构地区：[1]湖北省新华医院呼吸内科,湖北武汉430015

出　　处：《临床肺科杂志》2013年第11期2034-2036,共3页Journal of Clinical Pulmonary Medicine

摘　　要：目的探讨不明原因长期发热患者的病因。方法分析在我院住院诊治且符合不明原因发热诊断标准的388例患者的临床资料。结果 388例患者中经各种检查或诊断性治疗最终明确诊断者253例,确诊率为65.2%。病因:感染性疾病131例,占51.8%,其中结核病55例,占感染性疾病的42.0%(55/131);结缔组织病69例,占27.3%,成人still病占结缔组织病的30.3%(20/69);肿瘤37例,占14.6%,其中淋巴瘤占86.4%(32/37);其他疾病16例,占6.3%;原因未明者135例,占34.8%。结论感染性疾病仍然是不明原因发热的主要病因,结核病尤其是肺外结核占较大比例。肿瘤性疾病和结缔组织病在发热待查中也占有相当比例,淋巴瘤和成人still疾病是这两类疾病的主要病种。Objective To investigate the causes of patients with long-term fever of unknown origin （FUO）. Methods The clinical data of 388 patients with long-term FUO were retrospectively analyzed. Results 253 patients were given a confirmed diagnosis, and the confirmation rate was 65.2%. The most common causes of FUO were infectious diseases （51.8%）, with 55 cases of tuberculosis. 69 patients were suffered from connective tissue disease （27.3%）, which included 20 cases of adult Still＇s disease. 37 cases were diagnosed as malignancy, and 16 cases were due to other diseases. However, no definite diagnosis had been made in the remaining 135 cases （ 34. 8% ）. Conclusion The infectious diseases, especially tuberculosis, are still the most common causes of FUO, and CTD and malignancy are also major causes of FUO.

关 键 词：发热 原因不明 回顾性研究 

分 类 号：R441[医药卫生—诊断学]