2007-2011年新疆医科大学第五附属医院住院病人抗菌药物使用及细菌耐药性分析  

Utilization of antibacterials in inpatients and analysis of bacterial drug resistance of the Fifth Hospital Affiliated to the Xinjiang Medical University from 2007 to 2011

作　　者：陈静[1] 范芳芳 

机构地区：[1]新疆医科大学第五附属医院药剂科,乌鲁木齐830011 [2]新疆维吾尔自治区中医院药学部,乌鲁木齐830000

出　　处：《药学服务与研究》2013年第4期291-295,共5页Pharmaceutical Care and Research

摘　　要：目的:了解新疆医科大学第五附属医院住院病人抗菌药物的使用及细菌耐药情况,为临床合理应用抗菌药物提供参考。方法:对本院2007-2011年住院病人应用抗菌药物的种类、用药金额、用药频度(DDDs)、日均费用(DDC)以及细菌耐药情况进行统计和分析。结果:5年来,本院最常用的抗菌药物是头孢菌素类、青霉素类和喹诺酮类药物。其中头孢菌素类消耗量最大,用药金额相对较高,并且第三代及第四代头孢菌素使用量逐年增加,细菌耐药情况日趋严重。结论:本院抗菌药物的使用基本合理,但仍存在选药起点偏高等问题。医院应加大管理力度,使抗菌药物的使用更加安全、有效、合理、经济。Objective： To investigate the utilization of antibacterials in inpatients of the Fifth Hospital Affiliated to the Xin- jiang Medical University from 2007 to 2011 and also to analyze their bacterial drug resistance,so as to provide reference for ra- tional use of antibacterials. Methods： The categories,consumption sum,the frequency of medication （DDDs） and daily drug cost （DDC） of antibacterials used in the hospital from 2007 to 2011 were analyzed statistically. Results： The most frequently used antibacterials were cephalosporins, penicillins and quinolones from 2007 to 2011. Of all the antibacterials, the consumption of cephalosporins was the highest and its consumption sum was also relatively higher. Furthermore, the consumptions of the third and fourth generations of cephalosporins increased year by year, and bacterial resistance became more and more serious. Conclusion： The uti- lization of antibacterials in the hospital was on the whole rational,however,the problem of selecting high caliber antibacterials and other problems still existed. For this reason,greater efforts should be made on the part of the hospital in the management and control of drugs, so as to ensure that the utilization of antibacterials would be safer, more effective, rational and economical.

关 键 词：抗菌药物 用药频度 用药金额 细菌耐药 

分 类 号：R969.3[医药卫生—药理学] R978.1[医药卫生—药学]