胆囊胆固醇息肉与血脂的关系及用UDCA的治疗价值  

The relationship of cholesterol polyps of gallbladder and blood lipid and treating value of UDCA

作　　者：孟庆成[1] 张同琳[2] 

机构地区：[1]航天中心医院普通外科,北京100049 [2]北京大学第三医院普通外科,北京100083

出　　处：《中国现代医学杂志》2013年第22期38-42,共5页China Journal of Modern Medicine

摘　　要：目的探讨熊去氧胆酸(UDCA)治疗胆囊胆固醇息肉是否有效,并探讨胆固醇息肉与血脂的关系。方法从B超诊断为胆固醇性息肉的门诊病人中选择部分合适的病例进行UDCA治疗,进行一年的前瞻性观察,用B超检查比较服药前后息肉大小的改变,并观察其与血脂的关系。结果脂质代谢(包括三酰甘油和胆固醇)异常与胆固醇息肉无关;治疗组用药过程中息肉直径差异不具有显著性。胆囊息肉本身具有自行缩小、消失或增大的可能。结论胆固醇息肉与血脂无关,用UDCA治疗胆囊胆固醇息肉没有明显效果。[ Objective ] To explore weather ursodeoxycholic acid （UDCA） has the effect on cholesterol polyps of gallbladder and discuss its relationship with blood lipid. [ Methods ] The outpatients of cholesterol polyps diagnosed by ultrasound in hospital ,from whom the appropriate cases were selected for UDCA therapy, one-year prospective study to compare the size changes of polyp before and after the medication by B ultrasound and its relation with blood lipids was observed. [ Results ] Lipid metabolism （including triglycerides and cholesterol） unrelated to choles- terol polyps totally. The polyp size changes of treatment group showed that the diameter of polyps had no difference statistically. The polyps have the possibility of its own narrowing, increasing or disappear. [ Conclusions ] Cholesterol polyps has nothing with blood lipids. Treating cholesterol polyps using UDCA had no apparent effect.

关 键 词：熊去氧胆酸 胆囊胆固醇息肉 血脂 

分 类 号：R657.4[医药卫生—外科学]