玻璃酸钠结合功能锻炼对膝关节骨性关节炎的疗效  

Efficacy of sodium hyaluronate injection combined with exercise therapy on knee osteoarthritis

作　　者：张董喆[1] 

机构地区：[1]河南中医学院第二附属医院,河南省郑州市450002

出　　处：《实用医学杂志》2013年第18期2994-2995,共2页The Journal of Practical Medicine

基　　金：河南省教育厅科学技术研究重点项目(编号:12A360014)

摘　　要：目的:观察关节腔内注射玻璃酸钠配合功能锻炼治疗骨性关节炎的疗效。方法:将100例膝关节骨性关节炎患者随机分为2组,治疗组50例采用玻璃酸钠关节腔注射配合功能锻炼治疗,对照组50例采用口服塞来昔布治疗,两组按规定疗程治疗后比较Lequesne综合评分、临床疗效。结果:治疗后Lequesne综合评分治疗组(4.6±0.9)分,对照组(5.2±1.1)分(P﹤0.01),总有效率治疗组96.0%,对照组84.0%(P<0.05)。结论:采用关节腔内注射玻璃酸钠配合功能锻炼治疗膝关节骨性关节炎,疗效确切,副作用较少,值得在临床推广应用。Objective To observe the clinical efficacy of sodium hyaluronate injection combined with exercise therapy on knee osteoarthritis. Methods 100 patients with knee osteoarthritis were randomly divided into 2 groups, 50 patients in treatment group were treated with sodium hyaluronate injection and exercise therapy; and the other 50 patients in control group were treated with oral celecoxib. Lequesne scores and clinical efficacy after the required course of treatment in both groups were evaluated. Results The Lequesne scores in treatment group and control group were （4.6 ± 0.9） points and （5.2 ± 1.1） points, respectively （P 〈 0.01）. The total effective rate of treatment group and control group were 96.0% and 84.0%, respectively （P 〈 0.05）. Conclusions Sodium hyaluronate injection combined with exercise therapy for knee osteoarthritis had better curative effects and less adverse reactions, and was worth clinical application.

关 键 词：膝关节骨性关节炎 功能锻炼 玻璃酸钠注射液 

分 类 号：R684.3[医药卫生—骨科学]