肺毛霉菌病的再认识  

Pulmonary mucormycosis

作　　者：应琳[1] 周建英[1] 

机构地区：[1]310003杭州,浙江大学医学院附属第一医院呼吸内科

出　　处：《国际呼吸杂志》2013年第18期1422-1424,共3页International Journal of Respiration

基　　金：国家自然科学基金（81170038,81100051）

摘　　要：肺毛霉菌病是由毛霉菌引起的条件致病性感染,好发于免疫抑制人群.起病急,进展快,临床表现无特异性,可表现为发热、咳嗽、呼吸困难、胸痛等.肺部CT表现包括渗出、实变、结节、空洞、胸腔积液.确诊主要依靠支气管镜或肺穿刺病理活检.尽早采用外科手术或抗真菌药两性霉素B治疗能明显改善预后.Pulmonary mucormycosis, an opportunistic infection caused by the ubiquitous filamentous fungi of the Mucorales order of the class of Zygomycetes,often occurs in immunosuppressed patients. The clinical features of pulmonary mucormycosis are nonspecific, including refractory fever, nonproductive cough, progressive dyspnea, and pleuritic chest pain. The presence of infiltration, consolidation, nodules, cavities, and pleural effusion can be seen on computed tomography scans. The diagnosis still relies on histopathology and transbronchial lung biopsy. The antifungal therapy with amphotericin-B or surgical approach as soon as possible can improve prognosis.

关 键 词：肺毛霉菌病 诊断 治疗 两性霉素B 

分 类 号：R519[医药卫生—内科学]