艾滋病高发地区HIV感染孕产妇分娩情况及妊娠结局  

Delivery conditions and pregnancy outcomes among HIV-infected pregnant women in high AIDS incidence areas of China

作　　者：王前[1] 王临虹[2] 方利文[2] 张志慧[1] 王爱玲[1] 王芳[1] 王潇滟[1] 乔亚萍[1] 

机构地区：[1]中国疾病预防控制中心妇幼保健中心妇女保健部,北京100089 [2]中国疾病预防控制中心慢性非传染病控制中心

出　　处：《中国公共卫生》2013年第10期1417-1419,共3页Chinese Journal of Public Health

基　　金：国家"十五"科技攻关课题(2004BA719A03)

摘　　要：目的 了解中国部分艾滋病高发地区人类免疫缺陷病毒（HIV）感染孕产妇分娩相关情况及妊娠结局。方法 2005年1月＆mdash;2011年8月,对艾滋病相对高发的4省7个县（市、区）医疗保健机构发现的全部HIV抗体检测结果阳性、并且继续妊娠分娩的1 187例HIV感染孕产妇及所产1 205名新生儿情况进行问卷调查及随访管理。结果 1 187例HIV感染产妇中,在助产机构分娩者占96.0%,剖宫产占39.1%,妊娠期发生合并症和并发症比例从2005年的34.1%降至2011年的24.3%,呈逐年递减趋势（＆chi;2=6.856,P=0.009）;HIV感染产妇所娩1 205名胎儿的活产比例自2009年后均达100.0%,新生儿死亡比例在0.0%~1.5%,年度变化趋势差异均无统计学意义（均P〉0.05）。结论 HIV感染孕产妇剖宫产率、产科损伤性操作、妊娠期合并症和并发症等可能增加母婴传播风险的产科相关因素暴露水平仍然较高。Objective To examine delivery conditions and pregnancy outcomes among human immunodeficiency virus（HIV）infected pregnant women.Methods This study was a prospective observational cohort study.From 2005-2011,1 187 HIV infected mothers and 1205 newborns were investigated face to face in 7 counties or districts with high HIV prevalence.Results Among the 1 187 pregnant women,hospital delivery accounted for 96.0%（1 139/1 187）.The ratio of cesarean section among the women was 39.1%（456/1 166）.The rate of pregnancy complications decreased from 34.1% to 24.3% from 2005 to 2011（＆chi;2=6.856,P=0.009）.Neonatal death rate was between 0 and 0.5%.There were no siginificant differences observed in annual variation trend for delivery status and pregnancy outcome among the HIV-infected pregnant women.Conclusion Although maternal delivery outcome and neonatal health being improved continuously,the incidences of some obstetric factors such as cesarean delivery,obstetric risk operation,pregnancy complications which may increase the risk of mother-to-child transmission are still high.

关 键 词：艾滋病 母婴传播 分娩方式 产科因素 妊娠结局 

分 类 号：R173[医药卫生—妇幼卫生保健]