老年性骨质疏松症患者腰椎及髋关节骨矿含量及骨钙素变化相关性分析  

Correlational analysis among bone mineral content of the lumbar vertebrae and the hip joint and osteocalcin in senile patients with osteoporosis

作　　者：樊继波[1] 李莎[1] 丁小刚[1] 鄂建设[1] 王建刚[1] 蒋亚飞[1] 张睿[1] 覃勇[1] 

机构地区：[1]三峡大学第一临床医学院康复医学科,湖北宜昌443003

出　　处：《中国骨质疏松杂志》2013年第9期927-929,共3页Chinese Journal of Osteoporosis

基　　金：宜昌市科技发展与研发项目医疗卫生课题(A11301-13)

摘　　要：目的研究并分析老年性骨质疏松症患者不同年龄组腰椎及髋关节骨矿含量及其骨钙素相关性。方法选取2011年3月-2012年3月在我院收治入院确诊的患者86例。应用X线骨密度检测仪检测其腰椎及髋关节骨矿含量,放免法检测其骨钙素。应用SPSS13.0对比研究骨质疏松症患者腰椎及髋关节骨矿含量与骨钙素变化相关性分析。结果 86例骨质疏松症患者随着年龄的增长腰椎及髋关节骨矿含量呈下降的趋势,而血清骨钙素水平相对增高(P<0.05),差异有统计学意义。Person相关分析结果显示:血清骨钙素与腰椎及髋关节骨密度呈负相关(P<0.05),结论血清骨钙素在早期诊断骨质疏松症有一定的临床意义。Objective To study and analyze the correlation among bone mineral content of the lumbar vertebrae and the hip joint and serum osteoealcin in senile osteoporosis patients in different age groups. Methods Eighty-six patients, who were confirmed as osteoporosis in our hospital from March 2011 to March 2012, were selected. The bone mineral content of the lumbar vertebrae and the hip joint was detected using X-ray absorptiometry. Serum osteoealcin was detected using radioimmunoassay. The correlation among bone mineral content of the lumbar vertebrae and the hip joint and serum osteoealcin in osteoporosis patients was analyzed using a SPSS 13.0 software. Results Along with the increase of age, the bone mineral content of the lumbar vertebrae and the hip joint decreased in all 86 patients, while the level of serum osteocalein increased accordingly, and the difference was statistically significant （P 〈 0.05）. Pearson correlation analysis showed that serum osteocalcin was negatively correlated to the bone mineral content of the lumbar vertebrae and the hip joint （ P 〈 0.05 ）. Conclusion Serum osteocalcin level has certain clinical significance in the early diagnosis of osteoporosis.

关 键 词：骨质疏松症 骨矿含量 骨钙素 相关性研究 

分 类 号：R683[医药卫生—骨科学]