白念珠菌群体感应分子的研究现状  

Current Status of Research on Quorum Sensing Molecules in Candida Albicans

作　　者：王立霞[1] 

机构地区：[1]吉林省吉林市北华大学医学检验学院微生物学及微生物学检验教研室,吉林吉林132013

出　　处：《中国皮肤性病学杂志》2013年第10期1055-1057,共3页The Chinese Journal of Dermatovenereology

摘　　要：群体感应是细菌在繁殖过程中分泌的一些特定化学信号,他们可以启动某些基因的表达。近年来发现,在某些真菌,如组织胞浆菌、白念珠菌、啤酒酵母可产生群体感应分子。这些分子在真菌的致病性、生物膜形成、菌相转换等方面起重要作用。本文主要综述白念珠菌的群体感应分子的致病性、生物膜形成及菌相转换中的作用。Quorum sensing is a specific chemical signals secreted by the bacteria during reproduction and can initiate the expression of certain genes. In recent years, some fungi such as Histoplasma capsulatum, Candida albicans, Saccharomyces cerevisiae produce quorum-sensing molecules. These molecules play an important role in the pathogenicity of the fungal infection, membrane formation, yeast-hyphae transition. In this paper, we re- view the role of quorum sensing molecules in pathogenicity, membrane formation and yeast-hyphae transition in Candida albicans.

关 键 词：群体感应 法尼醇 酪醇 白念珠菌 

分 类 号：R379.4[医药卫生—病原生物学]