四君子汤加减配合替吉奥胶囊治疗晚期胃癌  

Clinical Analysis of Modified Sijunzi Decoction Combined with Tegafur Gimeracil Oteracil Potassium Capsule in Treating 20 Cases of Late Gastric Cancer

作　　者：孙士玲[1] 张红瑞[2] 周发祥[2] 

机构地区：[1]河南中医学院第一附属医院血液肿瘤科,郑州450000 [2]河南中医学院,郑州450046

出　　处：《中国实验方剂学杂志》2013年第18期309-312,共4页Chinese Journal of Experimental Traditional Medical Formulae

基　　金：河南省基础与前沿技术研究项目(102300410010)

摘　　要：目的:比较四君子汤加减配合替吉奥胶囊与单纯替吉奥胶囊对晚期胃癌患者的临床疗效、毒副作用及免疫功能的改变。方法:将40例晚期胃癌患者随机分为观察组(四君子汤加减加替吉奥胶囊组)与对照组(单纯替吉奥胶囊组)各20例,观察两组患者在近期疗效、免疫功能、不良反应及生活质量等方面的差异。结果:两组对比观察组近期疗效、生活质量及免疫功能均明显高于对照组(P<0.05);观察组毒副作用明显低于对照组(P<0.05)。结论:四君子汤加减联合替吉奥胶囊治疗晚期胃癌可提高疗效、减轻毒副作用,改善患者的免疫功能,提高患者的生活质量。Objective： To compare the clinical efficacy,toxic side effects and immune function between modified Sijunzi decoction combined with tegafur gimeracil oteracil potassium capsule and pure tegafur gimeracil oteracil potassium capsule in treating late gastric cancer.Method： Fourty cases of late gastric cancer patients were randomly divided into the observation group（modified Sijunzi decoction combined with tegafur gimeracil oteracil potassium capsule） and the control group（pure tegafur gimeracil oteracil potassium capsule） and the differences in the recent therapeutical effect,immune function,adverse reactions and the quality of life were observed.Result：.Comparisons of the effect,quality of life,and immune function of two groups showed the observation group was superior to the control group（P 0.05）;and toxic effects of the the observation group were significantly lower than these in the control group（P 0.05）.Conclusion： Modified Sijunzi decoction combined with tegafur gimeracil oteracil potassium capsule for the treatment of late gastric cancer can enhance the curative effect,reduce toxic effects,improve the immune function of patients,and increase the quality of life of the patients.

关 键 词：胃癌 替吉奥胶囊 四君子汤加减 

分 类 号：R287[医药卫生—中药学]