2010年版《中国药典》一部含丹参制剂的提取工艺分析  

Analysis of Extraction Technology for Preparations Containing Salviae Miltiorrhizae Radix Et Rhizoma in 2010 Edition of Chinese Pharmacopoeia

作　　者：江力[1] 朱盛山[1] 李苑新[1] 蔡延渠[1] 

机构地区：[1]广东药学院中药开发研究所,广州510006

出　　处：《中国实验方剂学杂志》2013年第19期361-364,共4页Chinese Journal of Experimental Traditional Medical Formulae

基　　金：广东省教育部产学研合作项目(2010B090400208)

摘　　要：将《中国药典》2010年版一部收录的含丹参成方制剂的提取方法分为水煎煮法、乙醇加热回流法、乙醇-水提取法三大类,通过列表分类进行工艺分析,揭示存在提取溶剂选择不当、提取时间过长、提取温度过高、提取次数过多等问题,不利于丹参制剂的产业化生产。选取一种高效低耗并适合产业化生产的丹参提取方法具有重要意义,同时为丹参制剂的工艺改进提供参考。Extraction methods of Salviae Miltiorrhizae Radix et Rhizoma from preparations in 2010 edition of Chinese Pharmacopoeia were divided into three categories, such as decoction method, ethanol refluxing method and ethanol-water extraction method, then through list classification to analyze processes, it revealed that existed improper selection of extraction solvent, excessive of extraction time, overtop of extraction temperature, extraction too many times and so on, these problems were not conducive to industrial production of preparations containing Salviae Miltiorrhizae Radix et Rhizoma, it was important to choose a suitable industrial production method for extracting Salviae Miltiorrhizae Radix et Rhizoma with efficiency and low consumption, at the same time, this article could provide a reference for process improvement of preparations containing Salviae Miltiorrhizae Radix et Rhizoma.

关 键 词：丹参 制剂 提取工艺 丹参酮IIA 丹酚酸B 

分 类 号：R283.6[医药卫生—中药学]