四种天然环烯醚萜衍生物与甲胺的呈色性能研究  

Research on the Color-forming Properties of Methylamine with Derivatives of Four Natural Iridoids

作　　者：苏晓迪[1] 丁克毅[1] 刘军[1] 

机构地区：[1]西南民族大学化学与环境保护工程学院,四川成都610041

出　　处：《皮革科学与工程》2013年第5期15-19,共5页Leather Science and Engineering

基　　金：国家自然科学基金项目"天然环烯醚萜及其类似合成产物的交联呈色机理和构效关系研究"(项目编号:21176202);西南民族大学研究生创新科研研一般项目(CX2013SP02)

摘　　要：选取京尼平苷、龙胆苦苷、獐牙菜苦苷、梓醇四种天然环烯醚萜,通过简单的结构修饰获得相应的衍生物,并考察它们与最简单的含伯胺基化合物———甲胺的呈色反应性能,通过紫外-可见光谱(UV-vis)分析它们所形成色素的颜色与其结构之间的关系。结果表明:(1)采用β-葡萄糖苷酶对京尼平苷酸进行水解,可以得到相应的苷元;但按照同样的方法处理梓醇,却得不到相应的苷元;通过苷交换的方法处理龙胆苦苷和獐牙菜苦苷,都可以的到相应的目标产物——甲基龙胆苦苷苷元和甲基獐牙菜苦苷苷元,但是用同样的方法处理梓醇,却得不到甲基梓醇苷元。这可能是由于梓醇特殊的结构引起的。(2)甲基龙胆苦苷苷元与甲基獐牙菜苦苷苷元的结构相似,它们与甲胺反应生成色素颜色也相似,都是亮黄色。但是,京尼平与京尼平苷酸苷元的结构也很相似,但是二者与甲胺反应生成色素的差别很大,前者是蓝黑色,后者是紫红色。这说明,环烯醚萜骨架上取代基的位置对呈色性能影响很大。Derivatives of four natural iridoids （geniposide, swertiamarin, gentiopicroside and catalpol） were obtained by structural modifications. The modification products were adopted to react with methylamine to investigate their color-forming properties, the relationship between color of the pigments and compounds＇ structure were analyzed via Ultraviolet-visible spectroscopy （UV-vis）. The results indicated that： （1） The corresponding aglycone could be obtained by the hydrolysis of geniposidic acid under the catalysis of ^-glucosidase, however, the same process could not happen for catapol; swertiamarin aglycone and methylswertimarin aglyeone could be obtained by swertiamarin and gentiopicroside reacted with methanol, how- ever, the same process could not happen for catapol. These reason might be reduced by the special structure of catapol. （2） Methygentiopicroside aglycone and methylswertimarin aglycone have a similar structure, and their pigments obtained from the reaction with methylamine is also similar--bright yellow; however, for geniposidic acid aglyeone and genipin, which also have a similar structure, their pigments obtained from the reaction with methylamine is different--one is dark blue and the other is purple red. This result indicated that, the position of substitute groups have key effection for the color of pigments formed.

关 键 词：环烯醚萜 衍生物 甲胺 呈色性能 

分 类 号：R284[医药卫生—中药学]