喜炎平注射液联用维生素C注射液治疗上呼吸道感染的实效分析  

Analysis of actual effects of combining Xiyanping injection with vitamin C injection in treatment of upper respiratory tract infection

作　　者：王志飞[1] 霍剑[2] 谢雁鸣[1] 

机构地区：[1]中国中医科学院中医临床基础医学研究所,北京100700 [2]中国人民大学,北京100872

出　　处：《中国中药杂志》2013年第18期3161-3165,共5页China Journal of Chinese Materia Medica

基　　金：国家"重大新药创制"科技重大专项(2009ZX09502-030);国家自然科学基金青年基金项目(81202776);国家中医药管理局中医药行业科研专项(200907001-5-6);中国中医科学院第7批自主选题项目(Z0255);中国中医科学院客座研究员联合创新研究项目(ZZ070817)

摘　　要：目的:探讨喜炎平注射液治疗上呼吸道感染时联用维生素C注射液是否会提高治愈率。方法:基于喜炎平注射液治疗上呼吸道感染的HIS数据,应用带协变量的倾向评分加权Logistic回归控制混杂因素并评价喜炎平注射液联用维生素C注射液与未联用维生素C注射液在治愈率上的差别。结果:带协变量的倾向评分加权Logistic回归结果显示联用与未联用2组在治愈率上没有显著性差异。结论:喜炎平注射液治疗上呼吸道感染时联用维生素C注射液可能并不能提高治愈率。Objective： To investigate whether Xiyanping injection associated with vitamin C injection will improve the cure rate of upper respiratory tract infection compared to treatment with Xiyanping injection alone. Method： The analysis was based on hospital information system（HIS） data. Patients were divided into two groups according to whether he or she accepted the addition of vitamin C to treatment with Xiyanping injection. We used the propensity score to balance confounding factors, and made confounding factors which cannot be balanced by the propensity score to act as covariate variables. Then Logistic regression was used to evaluate the effec- tiveness of the two groups. Result： There was no significant difference between the 2 groups. Conclusion： Compared with Xiyanping injection alone, using vitamin C in combination does not improve the treatment effectiveness of upper respiratory tract infection.

关 键 词：喜炎平 HIS 合并用药 实效研究 维生素C注射液 

分 类 号：R56[医药卫生—呼吸系统]