453例疑似预防接种异常反应监测情况分析  

Analysis of 453 Adverse Events Following Immunization cases

作　　者：冯磊[1] 王艳玲[1] 范学彬[2] 

机构地区：[1]吉林医药学院,吉林吉林132000 [2]吉林市疾病预防控制中心

出　　处：《中国伤残医学》2013年第9期67-69,共3页Chinese Journal of Trauma and Disability Medicine

摘　　要：目的：探讨预防接种异常反应发生的规律，评价疫苗的安全性，改善预防接种的服务质量，增强公众对预防接种的信心。方法：对2008～2011年吉林市疑似预防接种异常反应监测系统报告的453例接种一类疫苗后发生异常反应的病例进行统计分析。结果：453例疫苗接种异常反应病例中一般反应378例，异常反应53例，无疫苗事故；百白破无细胞疫苗报告例数最多为213例，占47．0％；≤1岁组异常反应例数为216例，占总例数的82％，2～6岁组72例，占15．9％；就医后痊愈者136例，占30．0％；好转者312例，占68．9％。结论：吉林市疾病预防控制中心自2008年使用AEFI监测系统以来，AEFI检测的敏感性明显提高，异常反应的防治效果显著。由于异常反应的发生原因是多方面的，还应从加强疫苗质量的监管、提高接种人员的培训等方面入手，进一步降低异常反应的发生率。Objective： To explore the causes of AEFI so as to find ways to reduce the AEFI incidence. Methods ： Statistical analysis was conducted for the 453 cases who had adverse events following immunization from 2008 to 2011 in Jilin city. Results：378 cases were commom,abnormal reaction were 53 cases,To DPT AEFI report the first number. Among them,targets aged≤1 year accounted for 82% ; Aged from 2 to 6 account for 15.9% ; 136 AEFIs were cured and 312 were getting better. Conclusion：The surveillance of AEFI information management system has good sensitivity in Jilin city, the AEFI monitoring sensitivity and timeliness is better. The causes for the adverse events are various. The quality of vaccines should be improved, training for inoculators must be strengthened, in order to reduce the incidence of the adverse events.

关 键 词：预防接种 异常反应 监测 

分 类 号：R683.4[医药卫生—骨科学]