不同提取方法对苦豆子中氧化槐果碱与槐果碱含量的影响  

Study on the effects of different extraction methods on the content of oxysopho carpine and sophocarpine of Sophora alopecuroides L.

作　　者：冷晓红[1] 陈海燕[1] 郭鸿雁[1] 李军[1] 

机构地区：[1]宁夏职业技术学院,银川750021

出　　处：《西北药学杂志》2013年第5期457-458,共2页Northwest Pharmaceutical Journal

基　　金：科技部国家科技支撑项目(编号:2011BAI05B04)

摘　　要：目的研究不同提取方法对氧化槐果碱与槐果碱含量变化的影响。方法采用HPLC法测定不同产地、不同提取条件的苦豆子样品中氧化槐果碱和槐果碱的含量。结果饱和氢氧化钠溶液能使氧化槐果碱转化,对槐果碱无影响。结论为苦豆子及制剂的质量控制以及氧化槐果碱的综合利用提供依据。Objective To study the effects of different extraction methods on the content of oxysophocarpine and sophocarpine from Sophora alopecuroides L.Methods HPLC was used for determing the content of oxysophocarpine and sophocarpine from different producing area and by different extraction methods.Results The saturated sodium hydroxide solution can change oxysophocarpine,but has no effect on sophocarpine.Conclusion The results provide a basis for the quality control of Sophora alopecuroides L.and its preparation.

关 键 词：氧化槐果碱 槐果碱 苦豆子 含量变化 

分 类 号：R284[医药卫生—中药学]