闹羊花中的两个新化合物(英文)  

Two new compounds from the flowers of Rhododendron molle

作　　者：陈绍农[1,2] 鲍官虎[3] 汪礼权[1] 秦国伟[1] 

机构地区：[1]中国科学院上海药物研究所,上海201203 [2]伊利诺大学芝加哥分校药学院,芝加哥 [3]教育部茶叶生物化学生物技术重点实验室,安徽农业大学,合肥230036

出　　处：《中国天然药物》2013年第5期525-527,共3页

基　　金：supported by the National Natural Sciences Foundation of China(No.30170104)~~

摘　　要：目的:研究中药闹羊花中的化学成分。方法:运用多种色谱方法进行分离和纯化,采用IR,UV,MS和1D,2D NMR技术进行结构解析。结果:从乙醇提取物中分得2个化合物,推定其结构分别为2α,10α-环氧-3β,5β,6β,14β,16β-五羟基-木藜烷和2,6-二羟基苯甲酸苯甲酯-6-O-α-L-鼠李糖基-(1 3)-β-D-葡萄糖苷。结论:两个化合物均为新化合物。AIM： To study the chemical constituents of the flowers of Rhododendron moUe. METHODS： Compounds were iso- lated by repeated chromatography over silica gel and Sephadex LH-20. Structures were elucidated based on spectral techniques, mainly 1D- and 2D-NMR and mass spectrometric analyses. RESULTS： Two compounds （1 and 2） were isolated. CONCLUSIONS： Com- pounds 1 and 2 were identified as two new compounds： 2α, 10α-epoxy-3β,5β,6β,14β,16α-hexahydroxy-grayanane and benzyl 2, 6-dihydroxybenzoate-6-O-α-L-rhamnopyranosyl-（1→3）-β-D-glucopyranoside, respectively.

关 键 词：闹羊花 杜鹃花科 木藜芦烷二萜 核磁共振 

分 类 号：R284.1[医药卫生—中药学]