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作 者:于建设[1] 石海霞[1] 都义日[1] 秦毅强[1] 解雅英[1]
机构地区:[1]内蒙古医科大学第一附属医院麻醉科,呼和浩特市010050
出 处:《临床麻醉学杂志》2013年第9期882-883,共2页Journal of Clinical Anesthesiology
摘 要:目的比较蒙古族与汉族全身麻醉气管插管应激反应。方法选择择期手术患者蒙古族(M组)、汉族(H组),每组100例,选择气管插管全身麻醉,观察并记录麻醉前(基础值,T1)、气管插管即刻(T2)、气管插管后1min(T3)、5min(T4)、10min(T5)时MAP、HR,同时采集中心静脉血样5ml应用酶联免疫方法(ELISA法)测定血浆肾上腺素(E)、去甲肾上腺素(NE)和多巴胺(DA)浓度。结果两组患者气管插管前各项指标比较差异无统计学意义。T2~T5时M组MAP、HR、E、NE、DA明显高于H组(P〈0.01)。结论蒙古族患者气管插管应激反应明显强于汉族患者。Objective To compare the stress response between Mongolia and Han during general anesthetic tracheal intubation. Methods Two hundred patients were divided into two groups according to the ethnics either Mongolian or Han with 100 each. MAP, HR and blood epinephrine (E), norepinephrine (NE) and dopamine (DA) levels were monitored at the following time points: prior to anesthesia (T1), immediately at the time of tracheal intubation (T2), 1 min (T3), 5 min (T4), and 10 min (T5) after tracheal intubation. Meanwhile, central venous blood samples 5 ml at the same time point, application of ELISA method were measured in plasma for E, NE and DA. Results There were no significant difference of MAP, HR, blood E, NE and DA levels before anesthesia between two groups. The values of MAP, HR, blood E,NE and DA level in the group M were higher than group H at the time of T2-T5 (P 〈 0. 01 ). Conclusion Stress response of the Mongolia patients is much higher than the Han patients during general anesthetic tracheal intuhation.
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