廉江地区妇女HPV感染与宫颈上皮内瘤变的研究  

Study of Lianjiang HPV Infection and Cervical Epithelial Neoplasia in Women

作　　者：郭翠河 王丽峰[1] 杨岚[1] 温都苏[1] 谭春燕[1] 杨冬[1] 徐兰兰[1] 

机构地区：[1]广东省廉江市人民医院妇科,广东廉江524400

出　　处：《航空航天医学杂志》2013年第9期1027-1028,共2页Journal of Aerospace medicine

摘　　要：目的:了解本地区HPV感染情况,分析HPV感染与宫颈上皮内瘤变的关系。方法:对500例妇女进行筛查,均行TCT、HPV分型检测和宫颈组织学活检,对检测结果进行分析,研究HPV感染与宫颈上皮内瘤变的相关性。结果:500例病人共检测出HPV阳性155人,阳性率为31%,单一亚型111例,占71.6%,双重亚型35例,占22.6%,三重亚型5例,占3.2%,多重亚型4例,占2.6%,结果具有统计学意义(P<0.05),155例HPV阳性病人中,检出18种HPV亚型,HPV16检出率最高,其次为HPV33和HPV58,结果具有统计学意义(P<0.05)。结论:廉江地区HPV感染主要亚型为HPV16、33、58、31、18,HPV16和HPV33感染是导致CINⅡ及CINⅢ的主要原因。Objective ：To understand the status of local HPV infection, and analyze the relationship between HPV infection and cervical intraepithelial neoplasia. Methods：For screening of 500 women, underwent TCT, HPV genotyping and cervical biopsy, carries on the analysis to the test results, the correlation of HPV infection and cervical intraepithelial neoplasia. Results ：500 patients were detected in 155 were HPV positive, the positive rate was 31%, single subtype 111 cases, accounting for 71.6%, double subtype 35 cases, accounted for 22.6%, three and 5 cases, accounting for 3.2%, multiple subtypes in 4 cases, accounting for 2. 6% , the results were statistically significant （ P 〈 0.05 ）, 155 cases of HPV positive patients, the detection of 18 kinds of HPV subtypes, HPV16 had the highest detection rate, followed by HPV33 and HPV58, the results were statistically significant （P 〈 0.05 ）. Conclusions ： HPV infection in Lianjiang area the main subtype HPV16, 33, 58, 31, 18, HPV16 and HPV33 infection is a major cause of CIN Ⅱ and CIN Ⅲ.

关 键 词：HPV感染 宫颈上皮内瘤变 相关性 

分 类 号：R711.74[医药卫生—妇产科学]