病愈猪免疫血清改善猪口蹄疫暴发中哺乳小猪的生存率  

Improvement of survival rate of breast-fed piglets in an outbreak of foot-and-mouth disease by immune serum obtained from a recovered pig

作　　者：郑宜翔[1] 马淑娟[1] 刘云岗[1] 

机构地区：[1]南方医科大学公共卫生与热带医学学院,广州510515

出　　处：《医学动物防制》2013年第9期949-951,954,共4页Journal of Medical Pest Control

基　　金：广东省高等学校人才引进专项基金资助项目(粤财教[2010]343号)

摘　　要：目的探讨免疫血清对哺乳小猪在口蹄疫(foot-and-mouth disease,FMD)流行过程中的作用。方法以FMD暴发流行中刚病愈的成年母猪的血清对新生小猪进行被动免疫,逐日观察其死亡率,并以邻近一受染猪场(拥有相同设施与管理但未作免疫处理)的小猪为对照。结果被动免疫显著降低了哺乳小猪的FMD死亡率;未注射免疫血清与注射了的猪场相比,哺乳小猪FMD死亡率由82.2%降至18.6%。结论本调查提示当FMD在饲养的猪中暴发时,免疫血清法可以显著改善哺乳小猪的生存率。Objective To explore the function of immune serum on foot-and-mouth disease（FMD） in the process of epidemic.Methods A passive immune measure was applied to the newborn domestic piglets by using the serum prepared from an adult female pig just recovered from FMD,and the death rate was monitored daily,with the piglets in a nearby affected farm（with identical facilities and management where no immune treatments were performed） as the comparison.Results This passive immune method greatly reduced the mortality of FMD in breast-fed piglets.The mortality of FMD in breast-fed piglets decreased from 82.2% to 18.6%.Conclusions This study suggests that when an outbreak of FMD in domestic pigs comes,the method of immune serum may significantly improve the survival rate of breast-fed piglets.

关 键 词：口蹄疫 免疫血清 被动免疫 哺乳小猪 

分 类 号：S858.28[农业科学—临床兽医学]