环己酮肟合成工艺的研究  

Study on Synthesis Process of Cyclohexanone Oxime

作　　者：赵巍[1] 左春山[1] 刘大勇[1] 张昕[1] 

机构地区：[1]黄淮学院化学化工系,河南驻马店463000

出　　处：《河北师范大学学报（自然科学版）》2013年第5期488-491,共4页Journal of Hebei Normal University：Natural Science

基　　金：河南省国际合作项目(094300510101);河南省科技发展计划重点科技攻关项目(092102310208)

摘　　要：通过单因素分析法和正交试验法,研究了pH、反应温度、反应时间、反应物物质的量之比等因素对环己酮肟合成的影响,得到了各因素影响环己酮肟收率的主次顺序,获得了环己酮肟合成的最佳工艺条件:pH为8,反应10min,反应温度45℃,n(盐酸羟胺)∶n(环己酮)=1.5∶1.在该条件下收率可达到87.9%.Effects of pH,reaction temperature,reaction time,reactant molar ratio for the cyclohexanone oxime synthesis were investigated in this paper by single-factor analysis and orthogonal test methods. The order of factors influencing on the yield was obtained. The optimum condition for cyclohexanone oxime synthesis were pH 8,reaction time of 30 min, reaction temperature of 45℃,and molar ration of n（hydroxyla mine hydrochloride） ： n（cyclohexanone）=1.5 ： 1. Under this condition,the yield of 87.9% is obtained.

关 键 词：氨肟化 环己酮肟 单因素分析法 正交实验法 

分 类 号：O625.6[理学—有机化学]