青岛地区部分医院2010—2012年嗜麦芽窄食假单胞菌感染分布及耐药性分析  

STENOTROPHOMONAS MALTOPHILIA INFECTIONS IN SOME HOSPITALS IN QINGDAO DURING 2010—2012:ANALISYS OF DRUG RESISTANCE AND INFECTION DISTRIBUTION

作　　者：邓华[1] 赵自云[1] 李莉[1] 

机构地区：[1]青岛大学医学院第二附属医院检验科,山东青岛266042

出　　处：《青岛大学医学院学报》2013年第6期546-547,549,共3页Acta Academiae Medicinae Qingdao Universitatis

摘　　要：目的了解青岛地区部分医院2010—2012年临床分离的嗜麦芽窄食假单胞菌的临床分布及其耐药性。方法对青岛市中心医疗集团所属各医院以及周边社区医院2010年1月1日—2012年12月31日分离的嗜麦芽窄食假单胞菌进行临床分布及耐药性分析。结果共分离出嗜麦芽窄食假单胞菌355株,检出率为0.65%;嗜麦芽窄食假单胞菌检出率呈逐年上升趋势。该菌在呼吸道标本中的检出率最高,达87.89%,主要分布于呼吸内科、肿瘤科、外科监护室、职业病科、血液科、烧伤科、神经内科等,对常用抗菌药的耐药率由高到低依次为头孢他啶(80.28%)、替卡西林-克拉维酸(79.15%)、复方磺胺甲唑(15.21%)、左氧氟沙星(14.08%)。结论青岛地区嗜麦芽窄食假单胞菌对复方磺胺甲唑和左氧氟沙星的耐药率较低,可以作为治疗嗜麦芽窄食假单胞菌感染的首选药物。Objective To investigate the clinical distribution and drug resistance of Stenotrophomonas maltophilia isola- ted （during 2010 2012） in some hospitals in Qingdao. Methods The clinical distribution and drug resistance of Stenotroph- omonas maltohilia isolated were analyzed. Results A total of 355 strains of Stenotrophomonas mahophilia were isolated, the detection rate being 0.65 %, increasing year by year. The detection rate was highest in respiratory-tract samples, reaching 87.89%, mainly distributed in department of respiratory, departments of oncology, and surgery, intensive care unit, occupational medicine, department of hematology, burn unit, and department of neurology, etc. The resistance rates （from high to low） were in the fol- lowing order= ceftazidime （80.28%）, ticarcillin/clavulanic acid （79.15%）, cotrimoxazole （15.21%）, and levofloxacin （14.08%）. Conclusion The resistance of Stenotrophomonas maltophilia in Qingdao area to cotrimoxazole and levofloxacin is lower, which can be used as the first choice drugs in the treatment of Stenotrophomonas maltophilia infection.

关 键 词：嗜麦芽窄食单胞菌 微生物敏感性试验 青岛 

分 类 号：R446.5[医药卫生—诊断学]