子宫腺肌病组织CD10的表达及意义  

THE EXPRESSION OF CD10 AND ITS SIGNIFICANCE IN ADENOMYOSIS

作　　者：闫丽萍[1] 尹相丛[2] 李明霞[1] 蔡慧慧[1] 

机构地区：[1]青岛大学医学院附属医院妇科,山东青岛266003 [2]青岛大学医学院附属医院血液病学研究室,山东青岛266003

出　　处：《齐鲁医学杂志》2013年第6期487-488,共2页Medical Journal of Qilu

摘　　要：目的探讨CD10在子宫腺肌病组织的表达及意义。方法采用免疫组化SP方法检测50例子宫腺肌病组织及其在位内膜组织和30例正常子宫内膜组织中CD10蛋白的表达情况。结果 CD10在正常子宫内膜、腺肌病组织及其在位内膜组织间质细胞中的阳性表达率分别为100%、98%和96%,各组间比较差异均无统计学意义(P>0.05)。结论 CD10可能是正常子宫内膜及异位子宫内膜间质细胞的一种敏感的免疫组化标志物,它可能为异位内膜的进一步生长提供相似的宫腔"土壤"环境,从而利于腺体的进一步生长。Objective To investigate expression of CD10 and its significance in adenomyosis. Methods The expres- sion of CD10 was detected by imrnunohistochemistry SP in 50 cases of adenomyosis and its eutopic endometrium and 30 cases of normal endometrial tissue. Results The expression rate of CD10 in the adenomyosis, its eutopic endometrium and normal endo- metrium was 100%, 98% and 96%, respectively （P〉0.05）. Conclusion CD10 is probably a susceptible immunohistochemical marker of normal endometrium and endometriotic stroma tissue, which is likely to provide an environment for the growth of the gland,

关 键 词：子宫 腺肌瘤 脑啡肽酶 

分 类 号：R711.74[医药卫生—妇产科学]