新疆维吾尔族、哈萨克族和汉族糖尿病前期人群血清尿酸及代谢综合征分布的横断面研究  

A cross-sectional study on serum uric acid level and the distribution of metabolic syndrome among Uigur, Han and Kazak prediabetic groups in Xinjiang

作　　者：张宏武[1,2] 蒋升[3] 徐焱成[1] 

机构地区：[1]武汉大学中南医院内分泌科,武昌430071 [2]新疆维吾尔自治区人民医院内分泌科 [3]新疆医科大学第一附属医院内分泌科

出　　处：《中华流行病学杂志》2013年第10期958-960,共3页Chinese Journal of Epidemiology

摘　　要：目的探讨新疆维吾尔（维）族、哈萨克（哈）族和汉族糖尿病前期人群血清尿酸水平、血压和血脂异常，分析代谢综合征和肥胖的分布。方法对30。80岁2053名维族、2219名哈族和2656名汉族居民进行糖尿病前期筛查，分析三组糖尿病前期人群代谢特点及比较组间差异。结果（1）共筛查出糖尿病前期患者1934例（28．3％），其中维族患病率最高（31．6％），哈族最低（25．5％），汉族居中（27．0％），组间比较差异有统计学意义（P=0．00）；（2）糖尿病前期患者高低密度脂蛋白胆固醇血症比例高达80．5％，高尿酸血症患病率为30．3％，代谢综合征患病率为58．3％，三组间比较差异无统计学意义（P〉0．05）；（3）糖尿病前期患者88．0％合并有高血压及高血压前期，其中哈族最高（96．8％），维族为85．1％，汉族为83．7％，组间比较差异有统计学意义（X^2=59．959，P=O．00）；（4）糖尿病前期患者合并肥胖总体为35．4％，汉族为29．6％，维族为36．8％，哈族为41．0％，组间比较差异有统计学意义（X2=19．097，P=0．00）。结论新疆维族、哈族和汉族人群糖尿病前期患病率存在差异，以维族人群最高；糖尿病前期人群中普遍存在血脂异常、高血压、高尿酸、代谢综合征及肥胖，其中哈族人群高血压患病率最高，维族人群肥胖患病率最高。Objective To explore the levels of uric acid, blood pressure, serum lipid metabolic disorders and the distribution of obesity and metabolic syndrome （MS） among Uygur, Han and Kazak pre-diabetic groups in Xinjiang. Methods A cross-sectional study was conducted on 2053 Uygur residents, 2219 Kazak residents and 2656 Han residents aged 30-80, all with prediabectic syndromes. The pre-dialectic patients were divided into three groups for analysis on metabolic features and inter-group comparisons. Results （ 1 ）In total, 1934 pre-diabetic cases （28.3%） were diagnosed, with the highest prevalence （31.6%） seen in Uygurs and the lowest （25.5%） in Kazaks and medium （27.0%） in Hans. Data from the inter-group comparison showed statistically significant differences （P=0.00）. （2） Prevalence of high LDL-C was 80.5%, with hyperuricemia as 30.3% and MS as 58.3%, while the inter-group comparison did not show any statistically significant differences （P〉 0.05）. （3）Prevalence of pre-diabetic when combined with hypertension or earlier-stage hypertension, reached 88.0%, with the highest （96.8%） among Kazak group, 85.1% in Uygurs and 83.7% in Han population. Data from the inter-group comparison showed statistically significant difference （Z~ = 59.959, P=0.00）. （4）The overall prevalence of prediabectic, when combined with obesity was 35.4%, with 29.6% in Han, 36.8% in Uygur and 41.0% in Kazak groups. Data from the inter-group comparison showed statistically significant difference （ Z2= 19.097, P=0.00）. Conclusion According to results from this cross-sectional study regarding the metabolic features of Uygur, Kazak and Han prediabectic groups, differences were seen in the prevalence rates of pre-diabetic among Uygur, Kazak and Han ethnic groups, with the highest seen in Uygurs and the lowest in Kazaks. Hyperlipidemia, hypertension,hyperuricemia, MS and obesity were commonly seen in all the prediabectic groups, with the highest prevalence of hypertension seen in the Kazak group and th

关 键 词：糖尿病前期 尿酸水平 维吾尔族 哈萨克族 

分 类 号：R587.1[医药卫生—内分泌]