某院西院病区2011-2012年强阿片类镇痛药使用趋势分析  

Analysis of the Utilization Trends of Strong Opioid Analgesics in West District of a Hospital during 2011-2012

作　　者：李国[1] 冯雷[1] 兰杨[1] 张元[1] 

机构地区：[1]中国医学科学院北京协和医学院北京协和医院药剂科,北京100730

出　　处：《中国药房》2013年第38期3588-3591,共4页China Pharmacy

摘　　要：目的:分析某院西院病区强阿片类镇痛药的应用概况及趋势,为临床合理用药提供参考。方法:对该院西院病区2011-2012年强阿片类镇痛药的品种、消耗量、用药金额和用药频度及各科室应用情况等进行统计分析。结果:强阿片类镇痛药口服制剂中盐酸羟考酮缓释片20、5 mg两个规格以及磷酸可待因片的使用量、用药金额、用药频度(DDDs)均呈逐年上升趋势;盐酸吗啡缓释片、盐酸吗啡片、芬太尼透皮贴剂、盐酸吗啡注射剂、哌替啶注射液呈下降趋势。强阿片类镇痛药中的口服制剂以及外用贴剂的使用科室主要分布于肿瘤内科病房、呼吸科病房(肺癌中心)、血液科病房(血液肿瘤组);哌替啶注射液使用主要以外科手术镇痛为主,略有下降。结论:按照我国《癌症疼痛诊疗规范(2011年版)》以及美国国立综合癌症网络(NCCN)、欧洲姑息治疗学会(EAPC)疼痛治疗指南要求,从笔者调查的强阿片类镇痛药的使用趋势分析中,反映出该院西院病区强阿片类镇痛药的使用基本合理。OBJECTIVE： To analyze the application profiles and trends of strong opioid analgesics in west district of a hospi- tal, and to provide reference for rational drug use in the clinic. METHODS ： The utilization of strong opioid analgesics in all depart- ments of the hospital during 2011- 2012 were analyzed statistically in respects of drug types, consumption quantity, consumption sum and DDDs. RESULTS： The amount, consumption sum and DDDs of Oxycodone hydrochloride tablets （20 mg, 5 mg） as well as Codeine phosphate tablets increased year by year in west district hospital. Those of Morphine hydrochloride sustained-release tab- lets, Morphine hydrochloride tablets, Fentanyl transdermal patch, Morphine hydrochloride injection and pethidine injection had de- clined. The oral formulations and topical patches of strong opioid analgesics were mainly used in oncology department, respiratory ward （lung cancer center） and hematology ward （blood cancer group） ; Pethidine injection was mainly used in surgical pain and it decreased slightly. CONCLUSIONS ： According to the requirements of pain treatment guidelines in Chinese Cancer Pain Treatment Specification （2011 edition）, U.S. Adult Cancer Pain Guidelines （NCCN） and the European Academy of Palliative Care （EAPC）, the use trends of strong opioid analgesics studied by the author are analyzed, which reflects the use of strong opioid analgesics in west district of the hospital is reasonable.

关 键 词：强阿片类镇痛药 用药趋势 合理用药 

分 类 号：R969.1[医药卫生—药理学] R971.1[医药卫生—药学]