临床药师参与1例儿童肾病综合征的药物治疗实践  

Participation of Clinical Pharmacist in the Therapeutic Protocol of a Case of Pediatric Nephrotic Syndrome

作　　者：张春[1] 陆晓彤[1] 刘海涛[1] 李方[1] 卜书红[1] 张健[1] 

机构地区：[1]上海交通大学医学院附属新华医院药剂科,上海200092

出　　处：《中国药房》2013年第38期3637-3639,共3页China Pharmacy

摘　　要：目的:探讨临床药师在参与儿童肾病综合征药物治疗方案调整中的作用。方法:通过1例个体化的儿童肾病综合征药物治疗方案合理性分析,临床药师从激素的治疗方案确定及不良反应监测、抗感染药物治疗优化、抗凝药物调整三方面提出用药分析及建议,调整完善患儿的治疗方案为:甲基强的松龙18 mg,q12h,ivgtt;头孢哌酮/舒巴坦0.9 g,q12h,ivgtt;加用小剂量双嘧达莫25 mg,tid,po。结果:医师接受临床药师提出的用药建议,患儿治疗过程顺利,病情好转出院。结论:儿童肾内科专业临床药师可以从原发病治疗方案及并发症的药物应用等多方面切入临床儿童专科的药物治疗调整,与医师形成良好沟通与互动,协助医师确立儿童个体化的治疗方案。OBJECTIVE： To investigate the role of clinical pharmacist in the adjustment of therapeutic protocol for pediatric nephrotic syndrome. METHODS： Based on the rationality analysis of individual therapeutic regimen for a case of pediatric nephrot- ic syndrome, clinical pharmacists put forward advices and analyzed drug use from the respects of the determination of therapeutic regimen, ADR monitoring, optimization of anti-infective therapy, the adjustment of anticoagulants. The adjusted therapeutic regi- men was as follows： methylprednisolone 18 mg, ql2h, ivgtt; cefoperazone/sulbactam 0.9 g, ql2h, ivgtt; small dose of dipyri- damole, t.i.d, p.o. RESULTS ： Physician accepted the advices of clinical pharmacists, and the patient experienced the treatment pro- cess smoothly and improved greatly to leave hospital. CONCLUSIONS： Clinical pharmacist in pediatric nephrology department should focus on the regulation of the treatment protocol from primary disease and complications, frequently communicate with phy- sicians and assist them to provide individual therapy.

关 键 词：临床药师 肾病综合征 用药建议 用药分析 

分 类 号：R985[医药卫生—药品] R969.3[医药卫生—药学]