新疆输入性疟疾13例临床特征分析  

Clinical characteristics analysis of 13 imported malaria cases in Xinjiang

作　　者：李玉革[1] 王凌冰[2] 陈访贤[3] 王晓蓉[2] 何冰[2] 

机构地区：[1]新疆医科大学第一附属医院,乌鲁木齐830011 [2]新疆国际旅行卫生保健中心 [3]新疆医科大学学生处

出　　处：《现代预防医学》2013年第19期3703-3704,共2页Modern Preventive Medicine

基　　金：新疆科技厅科技支撑项目:《新疆国境口岸重大传染病快速监测技术及防控措施的研究(201217153)》

摘　　要：目的探讨新疆输入性疟疾的临床特征,为临床医师早期诊治该疾病提供依据。方法回顾性分析新疆13例输入性疟疾的临床资料。结果输入性疟疾以恶性疟疾多见,发热多不规则,前期伴有头痛、肌肉酸痛、咳嗽等症状以及腹痛、腹泻、呕吐等消化道症状,可并发肝肾功能损害;实验室检查白细胞可明显升高,以中性粒细胞比值升高为主(7/13,53.85%),有(9/13,69.23%)的患者出现血小板下降;30.77%的输入性疟疾患者治愈后会出现再燃。5例患者表现为谷丙转氨酶(ALT)和谷草转氨酶(AST)的升高。5例患者表现为肌酐或尿素氮的升高。2例有肝肿大,6例有脾肿大。经蒿甲醚治疗后,13例患者均治愈。结论输入性疟疾临床表现复杂,并发症多,应对临床拟诊病人采取多次查找疟原虫的措施以及早期实验性抗疟治疗。OBJECTIVE To investigate the clinical features of imported malaria in Xinjiang, and provide the foundation for doctors to diagnose the disease. METHODS Retrospectively analyzed the clinical data on 13 cases of imported malaria. RE- SULTS Falciparum malaria was more than in imported malaria, there were more irregular fever, prophase associated with headache, muscle aches, cough and other symptoms and abdominal pain, diarrhea, vomiting and other gastrointestinal symptoms, may be complicated by liver and kidney dysfunction; laboratory tests showed the white blood cells increased sig- nificantly, especially the neutrophil ratio increased （7/13, 53.85% ）, 69.23% patients had thrombocytopenia; 30.77% of the patients would reburn who with imported malaria. 5 patients＇ ALT and AST increased, 5 patients＇ creatinine or blood urea nitrogen enhanced, and 2 patients of hepatomegaly and 6 patients of splenomegaly.13 patients were cured after artemether treatment. CONCLUSION Imported malaria has complicated clinical manifestations, and many complications, we should take multiple measures to find the parasite as well as early experimental antimalarial treatment.

关 键 词：输入性 疾病特征 新疆 

分 类 号：R531.3[医药卫生—内科学]