卵巢过度刺激综合征的研究现状  

Progress in Ovarian Hyperstimulation Syndrome

作　　者：姜李乐[1] 曹国昌[2] 梁琳琳[1] 张翠莲[1] 

机构地区：[1]郑州大学人民医院生殖医学研究所,450003 [2]河南科技大学药理学与医学分子生物学实验室

出　　处：《国际生殖健康／计划生育杂志》2013年第5期391-394,共4页Journal of International Reproductive Health/Family Planning

摘　　要：卵巢过度刺激综合征(OHSS)是一种外源性或内源性促性腺激素所致的综合征。主要与使用外源性促性腺激素有关,偶见于使用氯米芬促排卵者,自然周期妊娠者较罕见。近年来,随着无排卵型不孕症发病率的逐年增高,在体外受精-胚胎移植(IVF-ET)中,控制性超促排卵是必要步骤。OHSS渐渐成为辅助生殖技术(ART)最常见最具潜在危险的并发症。其不但影响胚胎着床发育,严重者还会危及患者生命。综述近几年来OHSS发病机制、临床表现、预防及治疗等方面的研究现状。Ovarian hyperstimulation syndrome （0HSS） is an exogenous or endogenous gonadotropin- induced syndrome. 0HSS is associated mainly with exogenous gonadotropin, occasionally with Clomiphene, rarely with the natural cycles of pregnancy. In recent years, with the increasing incidence of anovulatory infertility, the controlled ovarian hyperstimulation becomes a necessary step in in vitro fertilization and embryo transfer. OHSS gradually became one of the most common complications with potentially high-dangerous in assisted reproductive technology. 0HSS affects embryo implantation and embryo development, and it could be fatal in some severe cases. The research progress on the pathogenesis, clinical manifestations, prevention and treatment of OHSS were discussed in this review.

关 键 词：卵巢过度刺激综合征 促性腺素类 排卵诱导 受精 体外 胚胎移植 生殖技术 辅助 

分 类 号：R711.75[医药卫生—妇产科学]