FFA与OCT在年龄相关性黄斑变性诊断中的应用  

The application of fluorescent fundus angiography and coherent tomography in age-related macular degeneration

作　　者：陈雪芳[1] 刘忠鑫[1] 陈炳荣[1] 郑轶[2] 董丽[1] 

机构地区：[1]海南省三亚市人民医院眼科,572000 [2]哈尔滨医科大学附属第一医院眼科

出　　处：《中国实用眼科杂志》2013年第10期1315-1317,共3页Chinese Journal of Practical Ophthalmology

基　　金：黑龙江省青年科学基金（QC2011C131）

摘　　要：目的探讨荧光素眼底血管造影（FFA）联合相干光断层扫描（OCT）在年龄相关性黄斑变性（ARMD）检查中的联合应用价值。方法对于2012年3月至2012年10月在三亚市人民医院眼科门诊经FFA确诊的37例（59只眼）ARMD患者进行OCT检查，并统计检查结果。结果59只眼中，萎缩型42只眼（71．19％），渗出型17只眼（28．81％）。萎缩型表现均为点状或斑驳样透见荧光，未见荧光素渗漏。渗出型早期可见脉络膜新生血管（CNV）形态，晚期大量荧光素渗漏，周围有出血者则表现为荧光遮蔽。结论FFA和OCT在对ARMD的诊断上各具优势，FFA有助于发现可定位渗漏点，反映疾病的范围和部位，OCT可定性定量检查ARMD，两者结合可以更有效地诊断ARMD。Objective To explore the clinical significance of FFA （fluorescent fundus angiogra- phy） along with OCT （coherent tomography） in age-related macular degeneration （ARMD）. Meth-ods Thirty-seven patients （59 eyes） diagnosed ARMD by FFA were sent to OCT inspection and re-cord the results. Results In total of 59 eyes in 37 ARMD patients, 43 eyes （72.88%） were diag- nosed as atrophic type, 15 eyes （25.42%） exudative type. The atrophic type showed spots or mottled shape in fluorescence transmission, and no fluorescein leakage was found. In the early stage of exu-dative type, choroidal neovascularization （CNV） could be seen, and in the later stage, there was a lot of fluorescein leakage; the blocked fluorescence was observed if hemorrhage formed around. Conclusions Both FFA and OCT have advantage in diagnosing ARMD. FFA can point the leakage spots, and reflect the extent and location of disease. OCT can check ARMD qualitative and quantita-tive. Combination of FFA and OCT can better diagnose ARMD.

关 键 词：相干光断层扫描 荧光素眼底血管造影 年龄相关性黄斑变性 

分 类 号：R774.5[医药卫生—眼科]