阿霉素凝胶微球中阿霉素含量的测定  

Content Determination of Gel Microspheres Loading Adriamycin

作　　者：张卿[1] 于彩平[1] 李卓恒[1] 宋羿[1] 卢来春[1] 

机构地区：[1]第三军医大学大坪医院野战外科研究所药剂科,重庆市渝中区长江支路10号400042

出　　处：《光谱实验室》2013年第5期2192-2195,共4页Chinese Journal of Spectroscopy Laboratory

基　　金：国家国际科技合作专项(os2012GR0209);重庆市国际科技合作项目(cstc201110001)

摘　　要：建立阿霉素凝胶微球中药物含量的测定方法。采用分光光度法,确定检测波长为480nm,阿霉素在2—40Lg/mL浓度范围内呈良好的线性关系(r=0.9999);平均加样回收率为99.7%,RSD为0.97%。该方法简便易行,快速准确,可用于阿霉素凝胶微球中阿霉素的含量测定。The method for the content determination of gel microspheres loading Adriamycin was established. The contents of gel microspheres loading Adriamycin were determined by spectrophotometry. The linear range of adriamycin was 2--40ug/mL （r; 0. 9999）with an average recovery of 99.7 % （RSD-=0. 97 % ） at 480nm. The method is simple,accurate and rapid, which can be used in the quality control of gel microspheres loading Adriamycin.

关 键 词：阿霉素 凝胶微球 分光光度法 

分 类 号：O657.32[理学—分析化学]