微创手术治疗脊柱骨质疏松压缩性骨折的近期疗效分析  

Outcome analysis of minimally invasive spine surgical technique for osteoporotic vertebral compression fractures

作　　者：杨星华[1] 官正华[1] 韦溦[1] 张忠荣[1] 刘洋[1] 谢志坚[1] 叶峰[1] 田华科[1] 

机构地区：[1]解放军第三二四医院创伤显微外科,重庆400020

出　　处：《检验医学与临床》2013年第17期2277-2278,2280,共3页Laboratory Medicine and Clinic

摘　　要：目的研究微创手术治疗脊柱骨质疏松压缩性骨折的近期疗效。方法临床入选110例脊柱骨质疏松压缩性骨折患者,随机分成对照组和研究组,每组55例,其中对照组予以开放手术治疗;研究组采用经皮椎体后凸成形术(PKP)。治疗3个月后,比较分析两组患者的临床疗效。结果与对照组相比较,研究组的手术时间、出血量显著减少,差异具有统计学意义(P<0.05)。两组患者治疗前的视觉模拟评分(VAS)、SF-36、Oswestry伤残指数评定(ODI)及Cobb角差异均无统计学意义(P>0.05);与治疗前相比,各组治疗后的VAS评分、ODI及Cobb角均明显降低,差异有统计学意义(P<0.05),各组治疗后的SF-36均显著升高,差异有统计学意义(P<0.05);而治疗后,研究组的SF-36及Cobb角较对照组明显升高,差异有统计学意义(P<0.05),而两者治疗后的VAS评分、ODI差异均无统计学意义(P>0.05)。结论经皮椎体后凸成形术能够安全有效的治疗脊柱骨质疏松压缩性骨折,具有创伤小、手术时间短的优势,但需把握好适应证。Objective To explore the outcome of minimally invasive spine surgical technique for osteoporotic vertebral compression fractures .Methods 110 patients with osteoporotic vertebral compression fractures were ran-domly divided into percutaneous kyphoplasty （PKP） treatment group （PKP group ,55 cases） and open surgery treat-ment group （control group ,55 cases） ,and treated respectively .Clinical therapeutic effectiveness were compared be-tween the two groups three months after treatment .Results Compared with control group ,mean operating time and blood loss were significantly lower （P〈0 .05） .Compared with before treatment ,the VAS scores after treatment of ODI and Cobb Angle were significantly decreased ,and the SF-36 was significantly increased （P〈0 .05） .But after treatment ,SF-36 and Cobb Angle of PKP group were significantly increased than control group （P〈0 .05） ,while ODI and VAS score were with no statistical difference （P〉0 .05） .Conclusion PKP might be safe and effective for the therapy of spinal osteoporosis compression fractures with advantages of minimally invasive ,but indication should be considered .

关 键 词：骨质疏松症 脊柱压缩性骨折 开放手术 经皮椎体成形术 

分 类 号：R681.04[医药卫生—骨科学]