hCG注射后到授精时间间隔大于42小时对胚胎质量影响研究  

Effect of Embryo Quality on the Insemination Time Interval More than 42 Hours after the Injection of Human Chorionic Gonadotrophin

作　　者：柳胜贤[1] 牛吉峰[1] 倪佳[1] 黄静[1] 

机构地区：[1]郑州大学附属洛阳中心医院,河南洛阳471000

出　　处：《中国医学创新》2013年第27期8-10,共3页Medical Innovation of China

摘　　要：目的：探讨体外受精胚胎移植中hCG注射后授精时间间隔超过42 h对胚胎质量的影响。方法：将进行常规体外受精-胚胎移植519个周期的5493枚卵子分为两组,A组hCG注射后授精时间间隔大于42 h授精,B组hCG注射后授精时间间隔小于40 h授精,均于受精后16~18 h左右去除卵丘细胞观察授精的情况,分别统计并比较两组的受精率、卵裂率、优质胚胎率和可利用胚胎率。结果：两组的受精率、卵裂率、优质胚胎率、可利用胚胎率比较差异无统计学意义（P〉0.05）。结论：IVF-ET中取卵后在超过最佳授精时间授精并不影响胚胎的质量。Objective： To investigate the effect of embryo quality on the insemination time interval more than 42 hours after the injection of human chorionic gonadotrophin （ hCG ） in vitro fertilization and embryo transfer （ IVF-ET ） .Method： The 5493 eggs of the 519 cycles in the conventional IVF- ET were divided into two groups, group A was insemination in the insemination time interval more than 42 hours after the injection of hCG, and group B was insemination in the insemination time interval less than 40 hours after the injection of hCG.Observed the fertilization condition after removing the cumulus cells in 16-18 hours after fertilization, fertilization rate, cleavage rate, high quality embryo rate and the embryo rate of the groups were counted and compared respectively.Result： The fertilization rate, cleavage rate, high quality embryo rate and the embryo rate of two groups had no significant difference （ P〉0.05 ） .Conclusion： Insemination in exceeding the optimal insemination time after oocyte retrieval has no effect on the embryo quality in IVF-ET.

关 键 词：体外受精-胚胎移植 授精时间 胚胎质量 

分 类 号：R714.8[医药卫生—妇产科学]