思茅松松塔化学成分的初步研究  

Preliminary Study of the Chemical Constituents of Pinus Kesiya R. Pinecone

作　　者：施贵荣[1] 李冬梅[1] 杨静 刘熙[1] 李兆云[1] 刘光明[1] 

机构地区：[1]大理学院药学与化学学院,云南大理671000 [2]大理州食品药品检验所,云南大理671000

出　　处：《大理学院学报（综合版）》2013年第9期4-6,共3页Journal of Dali University

基　　金：国家自然科学基金资助项目(81260632)

摘　　要：目的:对思茅松松塔的化学成分进行初步研究。方法:采用溶剂法提取思茅松松塔的化学成分,运用正相硅胶、反相RP-18、Sephadex LH-20柱色谱和中压液相色谱等方法进行分离纯化,利用波谱数据鉴定化合物的结构。结果:从中分离鉴定了6个化合物,分别为:松脂醇(1),罗汉松树脂酚(2),(7S,8R)-3′,4,9,9′-四羟基-3-甲氧基-7,8-二氢苯并呋喃-1′-丙醇基新木脂素(3),dihydrodehydrodiconiferyl alcoho(l4),二氢槲皮素-3′-O-β-D-吡喃葡萄糖苷(5),3,4-二羟基苯甲酸(6)。结论:6个化合物均首次从该植物中分离得到。Objective： To study the chemical constituents of Pinus kesiya R. pinecone. Methods： The constituents were isolated and purified by extracting with system solution and using column chromatography with silica gel, RP-18, Sephadex LH-20 and MPLC. Their structures were identified by the spectral analysis. Results： Six compounds were isolated and identified as pinoresinol （1）, matairesinol （2）, cedrusin （3）, dihydrodehydrodiconiferyl alcohol （4）, 4＇,5,7-trihydroxyflavanonol-3＇-O-β-D- glucopyranoside （5）, and 3,4-dihydroxybenzoic acid （6）. Conclusion： These 6 compounds were obtained from P. kesiya for the first time.

关 键 词：思茅松 松塔 化学成分 木脂素 

分 类 号：R284[医药卫生—中药学]