IgG4相关性甲状腺疾病  

IgG4 Related Thyroid Diseases

作　　者：汪洵理[1] 黄秋实[1] 朱信心[1] 杜镇鸿[1] 陈强[1] 邓巧莲[1] 孙映荷[1] 陈锐[1] 魏涛[1] 刘枫[1] 马宇[1] 龚日祥[1] 李志辉[1] 朱精强[1] 

机构地区：[1]四川大学华西医院甲状腺乳腺外科,四川成都610041

出　　处：《中国普外基础与临床杂志》2013年第9期1075-1079,共5页Chinese Journal of Bases and Clinics In General Surgery

摘　　要：目的总结IgG4相关性甲状腺病与IgG4关系的研究进展。方法收集近年来国内外关于IgG4相关性甲状腺病的病理特征及其与IgG4关系的相关文献并作综述。结果 IgG4相关性疾病是一类新近被认识的与IgG4淋巴细胞密切相关的慢性、系统性疾病,可单发,也可累及甲状腺及全身多个器官。在桥本甲状腺炎、里德尔甲状腺炎及甲状腺乳头状癌病灶中均发现了IgG4的表达。结论 IgG4相关性甲状腺病是对甲状腺炎疾病的一种新的认识,对其的了解有助于对甲状腺炎患者提供合理的治疗手段。Objective To summarize the relationship between IgG4 and IgG4 related thyroid diseases. Methods Domestic and international publications involving the pathological features of IgG4-related thyroid diseases and relationship with IgG4 were retrieved and reviewed. Results IgG4-related disease was a newly recognized class of chronic and systemic lymphocytes disease, which may be solitary or involving multiple body organs, as well as thyroid. The expression of IgG4 was found in leisons of Hashimoto thyroiditis, Riedel thyroiditis, and papillary thyroid carcinoma. Conclusions IgG4-related thyroid disease is a new concept of thyroiditis. The knowledge of this new disease will provide appropriate treatment for patients with thyroiditis.

关 键 词：IgG4相关性甲状腺病 IGG4 桥本甲状腺炎 里德尔甲状腺炎 甲状腺乳头状癌 

分 类 号：R653[医药卫生—外科学] R581[医药卫生—临床医学]