替硝唑与甲硝唑分别联合阿奇霉素在术后感染急性盆腔炎中的应用效果比较  被引量:18

Comparison of efficacy of tinidazole or metronidazole combined with azithromycin in treatment of acute pelvic inflammatory disease caused by postoperative infections

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作  者:张淑珍[1] 李鼎恒 喻琴艳 桑霞[1] 

机构地区:[1]浙江萧山医院妇一科,浙江萧山311200

出  处:《中华医院感染学杂志》2013年第19期4782-4783,4831,共3页Chinese Journal of Nosocomiology

基  金:杭州市卫生科技计划项目(2012B044)

摘  要:目的探讨比较替硝唑与甲硝唑分别联合阿奇霉素在术后感染所致急性盆腔炎中的临床治疗效果,为临床治疗急性盆腔炎提供有效依据。方法选取2010年11月-2012年11月收治的108例术后感染所致急性盆腔炎患者,根据患者临床上所采用的治疗方法,将患者随机分为治疗组和对照组,每组54例。结果患者总有效率治疗组为94.44%、对照组为83.33%,组间比较,差异有统计学意义(P<0.05);实施治疗后,患者的盆腔包块面积治疗组为(5.12±0.45)cm2、对照组为(9.56±0.49)cm2,组间比较,差异有统计学意义(P<0.05)。结论在临床治疗术后感染所致急性盆腔炎的过程中,与甲硝唑联合阿奇霉素治疗方法相比较,采用替硝唑联合阿奇霉素治疗的临床效果较好,是临床上针对术后感染所致急性盆腔炎实施治疗的有效选择。OBJECTIVE To explore the effect of tinidazole or metronidazole combined with azithromycin on treatment of acute pelvic inflammatory disease caused by postoperative infections and provide effective basis for the clinical treatment of acute pelvic inflammatory disease. METHODS A total of 108 patients with acute pelvic inflammatory disease caused by postoperative infections admitted to the our hospital from Nov 2010 to Nov 201"2 were chosen as the research subjects. The patients were divided into the treatment group and the control group according to the treatment method, with 54 patients in each group. RESULTS There was significant difference in the total effective rate between the two groups ( 94.44% for the treatment group, and 83.33%for the control group) (P±0.05). After treatment, the pelvic mass in the treatment group was (5.12±0.45) em2 , significantly lower than the control group of (9. 56 ±0. 49) emz, and the comparison between groups was significant (P〈0.05). CONCLUSION In the process of clinical treatment, as compared with metronidazole combined with azithromycin, the clinical effect of. tinidazole combined with azithromyein is better on acute pelvic inflammatory disease caused by postoperative infections.

关 键 词:替硝唑 甲硝唑 阿奇霉素 术后感染 急性盆腔炎 

分 类 号:R978.1[医药卫生—药品]

 

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