幽门螺杆菌感染相关因素分析  

Related factors of Helicobacter pylori infections

作　　者：吴之茵[1] 夏瑾[1] 刘苹[1] 夏燕平[1] 

机构地区：[1]杭州市红十字会医院消化内科,浙江杭州310003

出　　处：《中华医院感染学杂志》2013年第20期4915-4916,共2页Chinese Journal of Nosocomiology

基　　金：国家自然科学基金青年基金(81102707)

摘　　要：目的分析幽门螺杆菌感染的相关因素,为预防和护理幽门螺杆菌感染提供依据。方法选择2012年诊治的胃部不适患者890例为调查对象,均采用14 C呼气试验检测幽门螺杆菌;根据检测结果将入选患者分为观察组和对照组,试验结果阳性的患者为观察组,试验结果阴性的患者为对照组,分析比较两组患者的相关因素。结果入选患者中幽门螺杆菌检测阳性患者共478例,阳性率为53.7%;其中男性266例,占55.6%,女性212例,占44.4%;≥30岁的患者幽门螺杆菌感染率明显高于<30岁的患者,差异有统计学意义(P<0.05);30～39、40～49、50～59岁和>60岁患者的幽门螺杆菌感染率比较,差异无统计学意义;性别、年龄观察组与对照组患者比较,差异无统计学意义;观察组患者饮生水、生食蔬菜、食用熏腌食物、吸烟、家族胃病史和有胃病史均显著高于对照组患者相应的指标,差异有统计学意义(P<0.01);观察组患者食用豆类及制品和食用大蒜均显著低于对照组患者相应的指标,差异有统计学意义(P<0.01)。结论胃部不适患者幽门螺杆菌感染率高,与患者的饮食、吸烟与否、家族和有胃部疾病史相关,提倡健康膳食,避免食用不洁食物和熏腌食品,及时戒烟,保持良好的心态,有利于预防幽门螺杆菌感染。OBJECTIVE To analyze the related factors of Helicobacter pylori （Hp） infections so as to provide bases for prevention and nursing of Hp infections. METHODS A total of 890 patients with stomach disorders who were treated in the hospital in 2012 were chosen as the research objects , then the Hp was detected through 1~C breath test , the patients were divided into the observation group with the positive testing result and the control group with the negative testing result, and the related factors were analyzed and compared between the two groups. RESULTS Of all the patients investigated, 478 cases were tested positive for Hp with the positive rate of 53.7~, including 266 （55.6~） cases of male patients and 212（44.4~） cases of female patients. The incidence rate of Hp infection was significantly higher in the patients aged more than 30 years than in the patients aged less than 30 years, the difference was significant（P^0.05）~ the difference in the incidence rate of Hp infections between the age groups of 30--39,40--49,50--59, and more than 60 was not significant. The difference in the gender or age between the observation group and the control group was not significant. The incidence rate of Hp infections was significantly higher in the patients of the observation group with drinking unboiled water, eating fresh vegetables, eating smoked pickled food, smoking history, family stomach disease history, and stomach disease history than in the patients of the control group with such indicators, the difference was significant（P%0.01） ~ the incidence rate of Hp infection was significantly lower in the patients of the observation group with eating beans and bean products or garlic than in the patients of the control group with such indicators, the difference was statistically significant（P d0.01）. CONCLUSION The incidence rate of Hp infections is high in the patients with stomach disorders ,which is related to the diet, smoking history, and family stomach disease history. It is an effective way to init

关 键 词：幽门螺杆菌 感染 相关因素 

分 类 号：R181.32[医药卫生—流行病学]