新城疫和鸡痘疫苗基础免疫对重组鸡痘活疫苗免疫效力的影响  

Protection Against Newcastle Disease Virus Induced by rFPV-ND-HN Vaccine in Chickens Vaccinated with Newcastle Disease and Fowlpox Vaccines

作　　者：甘天喻[1] 刘晓文[1] 甘军纪[1] 彭大新[1] 刘秀梵[1] 

机构地区：[1]扬州大学兽医学院,江苏扬州225009

出　　处：《中国家禽》2013年第19期19-21,共3页China Poultry

基　　金：江苏省高技术研究计划(BG2007336);江苏高校优势学科建设工程资助项目

摘　　要：本试验评价了新城疫(ND)疫苗和鸡痘(FP)疫苗免疫后对新城疫重组鸡痘病毒活疫苗(rFPV-ND-HN)免疫效力的影响。结果表明,用新城疫活疫苗和灭活疫苗进行基础免疫,不影响rFPV-ND-HN活疫苗的抗NDV免疫力的产生,但FP疫苗免疫后,再接种rFPV-ND-HN,免疫鸡既不能产生NDV HI抗体,也不能获得抗NDV强毒株攻击的保护力。Protective immunity against Newcastle disease virus （NDV） induced by recombinant fowlpox virus expressing NDV HN gene （rFPV-ND-HN） in chickens previously vaccinated with ND or fowl pox （FP） vaccines was evaluated. The results demonstrated that vaccination with ND live or inactivated vaccine in chickens before inoculation with rFPV-ND-HN did not interfere with the immune protection against NDV infection. However, when the chickens were vaccinated with FP vaccine and then vaccinated with rFPV-ND-HN,the HI antibody and the protection against NDV in chickens were not induced.

关 键 词：新城疫 重组鸡痘病毒 疫苗 免疫应答 

分 类 号：S852.65[农业科学—基础兽医学]