肾脏深度测算法对SPECT测定GFR影响的比较  

Comparison of different calculation on renal depth for measuring GFR by (99)~Tc^m- DTPA

作　　者：杨辉[1,2] 李文亮[1,2] 李德宇[1,2] 陈鸿彪[1,2] 周秀华[1,2] 李强[1,2] 

机构地区：[1]郑州大学附属肿瘤医院 [2]河南省肿瘤医院核医学科,郑州450008

出　　处：《医药论坛杂志》2013年第10期1-3,共3页Journal of Medical Forum

摘　　要：目的评价SPECT测定肾脏GFR时,肾脏深度不同测算方法的优劣。方法应用99Tcm-DTPA行SPECT测定GFR肿瘤患者共201例。分别通过CT测量、"新公式法"和Tonnesen法取得肾脏深度,并由Getes法取得相应的GFR;采用配对资料t检验,比较不同方法求得的肾脏深度及GFR。结果研究显示:通过CT测量与"新公式法"估算的肾脏深度、及其相应的GFR差异无统计学意义(P>0.05);通过CT测量与Tonnesen法估算的肾脏深度、及其所相应的GFR差异有统计学意义(P<0.05);"新公式法"估算与Tonnesen法估算的肾脏深度、及其相应的GFR差异有统计学意义(P<0.05);Tonnesen法低估了肾脏深度及GFR。结论在应用99Tcm-DTPA行SPECT检查测定GFR时,肾脏深度的确定,通过CT测量、采用"新公式法",准确性均优于Tonnesen法。Objective To assess the better method of detmnining the renal depth for the glomerular filtration rate （GFR） by single photon emission computed tomography（SPECT）. Methods Two hundred and one cases were selected from the cancer patients who undertook abdomen CT scanning and determined GFR by SPECT. The kidney depth was determined respectively by CT scanning, ＂new formula method＂ and Tonnesen method. The corresponding GFR was ob- tained by Gates method. The different sources of kidney depth and GFR were analyzed by Paired - sample T Test. Re- suits The study showed ： No significant differences statistically of the kidney depth and corresponding GFR between CT method and ＂new formula method＂. There were significant statistical differences of the kidney depth and corresponding GFR between CT method and Tonnesen method. There were significant differences of the kidney depth and corresponding GFR between ＂new formula method＂ and Tonnesen method. The kidney depth and the GFR were underestimated by Tonnesen method. Conclusion Determining the kidney depth for GFR by SPECT, the CT method and ＂new tormula method＂ were more accurate than Tonnesen method（plferred CT）.

关 键 词：肾脏深度 肾小球滤过率 体层摄影术 发射型计算机 单光子 

分 类 号：R692[医药卫生—泌尿科学]