中药运用对膀胱癌介入化疗术后不良反应的影响  

Traditional Chinese Medicine on Postoperative Adverse Reaction of Bladder Cancer Interventional Chemotherapy

作　　者：赵红星[1] 

机构地区：[1]湖州市第一人民医院放射介入科,湖州浙江31300

出　　处：《中华中医药学刊》2013年第10期2257-2259,共3页Chinese Archives of Traditional Chinese Medicine

基　　金：浙江省医药卫生一般科研项目B类资助项目(2012KYB199);浙江省医药卫生科技创新资助项目

摘　　要：目的:探讨运用中药对膀胱癌介入化疗术后不良反应发生情况的影响。方法:将104例临床确诊并行膀胱癌介入化疗术结合经尿道电切术的患者随机分为实验组和对照组,每组57例。实验组于介入术后水化输液,并增加运用中药治疗,对照组于介入术后单纯水化输液治疗。比较两组患者术后不良反应发生率及发生持续时间。结果:实验组在发热、骨髓抑制、胃肠道副反应、肝肾功能损害、皮疹脱发、轻度心电图改变等不良反应发生率与对照组无显著差异(P>0.05),不良反应发生持续时间短,差异有显著统计学意义(P<0.05)。结论:膀胱癌介入灌注化疗术后加用中药治疗能显著减少患者不良反应的持续时间,适合推广运用。Objective ： To investigate the application of traditional Chinese medicine on postoperative adverse reaction conditions of bladder cancer interventional chemotherapy. Methods ： 104 cases of bladder cancer with interventional chem- otherapy combined with concurrent transurethral prostatectomy patients were randomly divided into experimental group and control group,57 cases in each group. In the experimental group after intervention in the hydration fluid, traditional Chi- nese medicine treatment was used; control group patients after interventional treatment were given pure water infu- sion. Comparison of adverse reaction incidence and duration in two groups was carried on. Results： The fever,bone mar- row suppression, adverse reaction of gastrointestinal tract, liver and kidney function damage, hair loss, skin rash, mild elec- trocardiographic changes in experimental group and control group had no significant difference （ P 〉 0. 05 ）, the adverse reactions of short duration were statistically significant （ P 〈 0. 05）. Conclusions ： Bladder cancer interventional perfusion chemotherapy combined with traditional Chinese medicine treatment after operation can decrease patients＇ adverse reac- tion duration, which is suitable for promotion and application.

关 键 词：膀胱肿瘤 化疗 中药 不良反应 

分 类 号：G94[文化科学]