机构地区:[1]浙江大学医学院附属邵逸夫医院放射科,杭州310016
出 处:《中华放射学杂志》2013年第10期892-897,共6页Chinese Journal of Radiology
基 金:浙汀省科技厅科技计划项目(2010C33106);浙汀省教育厅项目(Y201017413)
摘 要:目的 比较团注对比剂跟踪技术和小剂量团注测试技术对第二代双源CT双能量肺灌注扫描成像质量和伪影的影响.方法 对60例临床疑似肺动脉栓塞的患者,采用第二代双源CT行双能量肺灌注扫描,根据随机表法将患者随机分为2组,每组30例.使用60 ml对比剂,扫描延迟时间分别采用团注对比剂跟踪技术(B组)和小剂量团注测试技术(T组)确定,2名影像医师测量并统计比较各目标血管(锁骨下静脉、上腔静脉、左心房、肺动脉主干、肺动脉S1段及S10段)的CT值、肺组织增强幅度、CT肺动脉成像(CTPA)图像质量主观评分及肺灌注图像伪影主观评分.采用Student t检验、方差分析、四格表卡方检验、非参数秩和检验、Kappa一致性检验进行统计学分析.结果 B组与T组比较,锁骨下静脉[(1042 ±639)、(2200±724) HU,F=43.196,P=0.001]、上腔静脉[(529±237)、(904±329) HU,F=25.654,P=0.001]、肺动脉主干[(325±112)、(383±69) HU,F=5.94,P=0.018]、肺动脉S1段[(320±118)、(385±73) HU,F=6.549,P=0.013]及肺动脉S10段[(307±78)、(360±82) HU,F=6.658,P=0.012]CT值均低于T组;左心房的CT值B组高于T组[(270±53)、(219±57) HU,F=12.823,P=0.001].肺动脉主干CT值高于诊断需求CT值(>250 HU)的比例B组低于T组[21例(70.0%)和29例(96.7%),x2=5.88,P<0.05].B组肺组织增强幅度均低于T组[右肺(29±8)和(34±8) HU,t=-2.401,P=0.020;左肺(30±7)和(36±9)HU,t=-2.493,P=0.016;全肺(30±7)和(35±8) HU,t=-2.495,P=0.016].B组的肺动脉成像质量评分4.4分,低于T组的4.9分(U=619.5,P<0.05),在2名观察者间取得了较好的一致性(kappa=0.708).B组肺灌注图像伪影评分为3.9分,高于T组的2.6分(U=162.5,P<0.05),在2名观察者间取得了较好的一致性(Kappa=0.796).结论 在使用60 ml对比剂的情况下,小剂量团注测试技术比团注对比剂跟踪技术能获得更Objective To compare the test bolus technique with the bolus tracking technique for dual-energy CT pulmonary angiography in patients suspected of pulmonary embolism (PE).Methods A total of 60 patients were randomized into 2 groups:bolus tracking technique group (group B,n =30) and test bolus technique group (group T,n =30).A standard dual-energy CT pulmonary angiography (CTPA)was performed after injection of 60 ml contrast medium followed by 35ml saline chaser at a speed of 4 mL/s.Attenuation profiles of different vascular segments (the subclavian vein,superior vena cava,left atrium,pulmonary trunk,S1 and S10 pulmonary artery) and enhancement value of lung parenchyma were measured to evaluate the timing techniques.The overall image quality of CTPA and pulmonary perfusion were analyzed by two radiologists.SPSS 19.0,Student t test,ANOVA test,Chi-Square test,Mann-Whitney U test and Kappa test were used for the statistic analysis.Results The attenuation of the subclavian vein [(1042 ± 639),(2200 ± 724) HU,F =43.196,P =0.001],superior vena cava [(529 ± 237),(904 ± 329)HU,F=25.654,P=0.001],pulmonary trunk [(325 ±112),(383±69)HU,F=5.94,P=0.018],S1 pulmonary artery [(320 ± 118),(385 ±73) HU,F =6.549,P =0.013],S10 pulmonary artery [(307 ± 78),(360 ± 82) HU,F =6.658,P =0.012] in group B were lower than those in group T,while the attenuation of the left atrium in group B was higher than that in group T [(270 ± 53),(219 ± 57)HU,F=12.823,P =0.001].The percentage of pulmonary arteries exceeding optimal attenuation (〉 250 HU) in groups B was lower than that in group T [n =21 (70.0%),n =29 (96.7%),x2 =5.88,P 〈 0.05].The enhancement value of pulmonary parenchyma in group B was lower than that in group T (the right lung (29±8)vs(34±8) HU,t=-2.401,P=0.020; the left lung (30±7)vs(36±9)HU,t=-2.493,P=0.016; total (30 ±7)vs(35 ±8) HU,t =-2.495,P =0.016).The image quality of CTPA in group B was poorer than
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