磁共振弥散加权成像在直肠癌诊断及预后中的应用研究  

Diffusion-weighted MR Imaging for Diagnosis and Prognosis in Rectal Cancer

作　　者：钟锐[1] 崔春艳[1] 郑小丽[1] 彭艳霞[1] 刘立志[1] 李立[1] 

机构地区：[1]华南肿瘤学国家重点实验室,中山大学肿瘤防治中心医学影像介入中心,广东广州510060

出　　处：《中国CT和MRI杂志》2013年第5期69-71,110,共4页Chinese Journal of CT and MRI

摘　　要：目的探讨磁共振(MR)扩散加权成像(DWI)在直肠癌诊断及预后中的应用研究。方法经病理证实为直肠癌患者52例和无直肠病变的对照组32例,全部行盆腔常规序列和DWI,获取ADC图。测量直肠癌和正常肠壁的表观扩散系数(ADC)值,进行统计学分析。结果直肠癌和正常肠壁ADC值间差异有统计学意义(t=10.932,P<0.01)。CEA水平与ADC值不相关。中分化与高分化直肠癌的ADC值比较差异有统计学意义(P<0.05)。结论直肠癌原发灶的ADC值明显低于正常直肠肠壁的ADC值。不同分化程度的直肠癌的ADC值间有统计学差异。Objective To explore the value of the diagnosis and prognosis in rectal cancer with magnetic resonance imaging （MRI） diffusion-weighted imaging （DWI）. Methods 52 patients with rectal cancer and 32 control group perform pelvic routine sequences and DWI and obtain ADC. The apparent diffusion coefficient （ADC） in rectal cancer and normal bowel wall were measuree and analyzed. Results The ADC of rectal cancer was higher than that of control group （t=10.932, P〈0.01 ）. There was no significant difference in between mean CEA levels and ADC, bur There was significant difference in between moderately differentiated and well-differentiated rectal cancer（P〈0.05）. Conclusion The ADC value of rectal tumor was significantly lower than that of normal bowel wall. There was significant difference in the degree of differentiation of rectal cancer.

关 键 词：磁共振成像 直肠癌 弥散加权成像 表观弥散系数 

分 类 号：R445.2[医药卫生—影像医学与核医学] R735.37[医药卫生—诊断学]