Synthesis and characterization of macrocyclic compounds with a hydroxyl functional group  

作　　者：Min Ou Chun Zhu Qi-Long Zhang Bi-Xue Zhu 

机构地区：[1]Key Laboratory of Macrocyclic and Supramolecular Chemistry,Guizhou University [2]Department of Chemistry,Guiyang Medical College

出　　处：《Chinese Chemical Letters》2013年第10期869-872,共4页中国化学快报（英文版）

基　　金：supported by the National Natural Science Foundation of China(No.21061003);he International Collaborative Project of Guizhou Province(No.[2009]700104);the Natural Science Foundation of the Guizhou Province(No.(2012)2151)

摘　　要：A novel [1＋1] Schiff-base macrocyclic compound 3 has been synthesized from precursor 1, 1,3-bis（2＇- formylphenoxy）-2-propanol, and precursor 2, resorcinol-bis（4-aminophenyl）ether, via condensation and cyclizaction using Ba2＋ as template. The macrocycle 3 was further reduced giving saturated macrocycle 4. The structures of 3 and 4 were characterized by elemental analysis, ~H NMR, IR, and MS spectra, and their structures were determined via single crystal X-ray diffraction studies. X-ray diffraction analysis revealed that the macrocyclic compound 3 has a folded conformation, and the corresponding reduced product 4 adopts a twisted and folded conformation due to its flexible nature. ~ 2013 Bi-Xue Zhu. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.A novel [1＋1] Schiff-base macrocyclic compound 3 has been synthesized from precursor 1, 1,3-bis（2＇- formylphenoxy）-2-propanol, and precursor 2, resorcinol-bis（4-aminophenyl）ether, via condensation and cyclizaction using Ba2＋ as template. The macrocycle 3 was further reduced giving saturated macrocycle 4. The structures of 3 and 4 were characterized by elemental analysis, ~H NMR, IR, and MS spectra, and their structures were determined via single crystal X-ray diffraction studies. X-ray diffraction analysis revealed that the macrocyclic compound 3 has a folded conformation, and the corresponding reduced product 4 adopts a twisted and folded conformation due to its flexible nature. ~ 2013 Bi-Xue Zhu. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.

关 键 词：Schiff base Macrocyclic compound Synthesis Structure 

分 类 号：O621.25[理学—有机化学]