Tetrazole-1-acetic acid as a ligand for copper-catalyzed N-arylation of imidazoles with aryl iodides under mild conditions  

作　　者：Feng-Tian Wu Ping Liu Xiao-Wei Ma Jian-Wei Xie Bin Dai 

机构地区：[1]School of Chemistry and Chemical Engineering/the Key Laboratory for Green Processing of Chemical Engineering of Xinjiang Bingtuan,Shihezi University

出　　处：《Chinese Chemical Letters》2013年第10期893-896,共4页中国化学快报（英文版）

基　　金：supported fnancially by the National Basic Research Program of China(973 Program,No.2012CB722603);the Start-Up Foundation for Young Scientists of Shihezi University(Nos.RCZX201012,RCZX201014,RCZX201015)

摘　　要：Tetrazole-l-acetic acid was found to serve as a superior ligand for Cul-catalyzed N-arylation of imidazoles with aryl iodides under a low catalyst loading （5 mol% of Cul）. A variety of aryl iodides could he aminated to provide the N-arylated products in good to excellent yields without the need of an inert atmosphere.Tetrazole-l-acetic acid was found to serve as a superior ligand for Cul-catalyzed N-arylation of imidazoles with aryl iodides under a low catalyst loading （5 mol% of Cul）. A variety of aryl iodides could he aminated to provide the N-arylated products in good to excellent yields without the need of an inert atmosphere.

关 键 词：Tetrazole-l-acetic acid N-Arylation Imidazoles Copper Aryl iodides 

分 类 号：O621.36[理学—有机化学]