利福平致急性肾衰竭并溶血性贫血1例  

1 Case Report of Rifampicin-associated Acute Renal Failure and Hemolytic Anemia

作　　者：吴珊珊[1] 张泽伟[1] 林春燕[1] 

机构地区：[1]揭阳市人民医院,广东揭阳522000

出　　处：《今日药学》2013年第9期617-618,共2页Pharmacy Today

摘　　要：1例50 a女性患者因内痔出血局部注射消痔灵注射液20 mL,顿服利福平胶囊0.45 g,第2日出现恶心、呕吐、尿量减少症状。实验室检查:RBC 2.7×1012/L,WBC 29.06×109/L,PLT 80×109/L,ALT 92 U/L,AST 83 U/L,TBIL26.6μmol/L,BUN27.55 mmol/L,Cr716μmol/L。考虑肝肾功能损害及溶血性贫血可能与利福平有关。予以血液透析、抗炎、利尿、护肝治疗30 d后好转出院。A 50-year old female rifampin 0.45 g. The next day, showed ： RBC 2.7 × 1012/L, WBC BUN 27.55 mmol/L, and Cr 716 rifampicin. After the treatment of discharged. patient treated by local injection of Xiaozhiling to cure internal hemorrhoid and taking she showed symptoms of nausea, vomiting, and less urines. Laboratory inspection 29.06× 109/L, PLT 80 × 109/L, ALT 92 U/L, AST 83 U/L,TBIL 26.6 μmol/L, μmol/L. The liver and renal function blood dialysis, anti-inflammatory, die damage and hemolytic anemia may induced by resis, and liver protect, she was improved and

关 键 词：利福平 不良反应 急性肾衰竭 溶血性贫血 

分 类 号：R97[医药卫生—药品]