Preparation of Elemental Tellurium Nanoparticles-Sucrose Sol and Its Antioxidant Activity in Vitro  

作　　者：李云志 PAN Jie JIANG Kun ZHOU Yanhui HUANG Jietao YE Jinxuan 白燕 

机构地区：[1]Department of Chemistry,College of Life Science and Technology,Jinan University

出　　处：《Journal of Wuhan University of Technology(Materials Science)》2013年第5期1048-1052,共5页武汉理工大学学报（材料科学英文版）

基　　金：Funded by the National Natural Science Foundation of China(No.21075053)

摘　　要：The elemental tellurium nanoparticles （TeNPs） - sucrose sol was prepared by the reaction of sodium tellurite with ascorbic acid in sucrose aqueous solution. The results indicated that TeNPs were dispersion excellent in the TeNPs - sucrose sol and the morphology of TeNPs was needle-like with about 70 nm in width and 500 nm in length. The antioxidant activity of the TeNPs - sucrose sol in vitro was estimated by pyrogallol autoxidation method, Fenton method and oxygen radical absorbance capacity （ORAC） assay. The results showed that a certain amount of TeNPs - sucrose sol could effectively scavenge superoxide anion free radical and hydroxyl free radical with scavenging rates of 73 % and 57 %, respectively. ORAC assay was used to measure the total antioxidant capacity of TeNPs - sucrose sol. The order of ORAC values was 2.25 μmol.L-1 TeNPs - 0.025 % sucrose sol 〉 0.025 % sucrose 〉 2.25 μmol.L-1 Na2TeO3 〉 1.63 μmol.L-1 ascorbic acid. The results suggested that the TeNPs - sucrose sol had the excellent antioxidant activity and TeNPs were the dominating contributors to antioxidant capacity of the TeNPs - sucrose sol.The elemental tellurium nanoparticles （TeNPs） - sucrose sol was prepared by the reaction of sodium tellurite with ascorbic acid in sucrose aqueous solution. The results indicated that TeNPs were dispersion excellent in the TeNPs - sucrose sol and the morphology of TeNPs was needle-like with about 70 nm in width and 500 nm in length. The antioxidant activity of the TeNPs - sucrose sol in vitro was estimated by pyrogallol autoxidation method, Fenton method and oxygen radical absorbance capacity （ORAC） assay. The results showed that a certain amount of TeNPs - sucrose sol could effectively scavenge superoxide anion free radical and hydroxyl free radical with scavenging rates of 73 % and 57 %, respectively. ORAC assay was used to measure the total antioxidant capacity of TeNPs - sucrose sol. The order of ORAC values was 2.25 μmol.L-1 TeNPs - 0.025 % sucrose sol 〉 0.025 % sucrose 〉 2.25 μmol.L-1 Na2TeO3 〉 1.63 μmol.L-1 ascorbic acid. The results suggested that the TeNPs - sucrose sol had the excellent antioxidant activity and TeNPs were the dominating contributors to antioxidant capacity of the TeNPs - sucrose sol.

关 键 词：tellurium nanoparticles - sucrose sol superoxide anion free radical hydroxyl free radical oxygen radical absorbance capacity （ORAC） 

分 类 号：O613.53[理学—无机化学]