天津市第一中心医院1161例住院患者抗菌药物临床应用横断面调查  

Cross-sectional survey on utilization of antibiotics among 1161 inpatients in Tianjin First Central Hospital

作　　者：王屏[1] 赵学群[1] 刘莉[1] 

机构地区：[1]天津市第一中心医院,天津300192

出　　处：《现代药物与临床》2013年第5期776-779,共4页Drugs & Clinic

摘　　要：目的调查分析天津市第一中心医院抗菌药物应用情况。方法采用横断面调查方法,对天津市第一中心医院2012年8月1日0：00~24：00时所有住院患者进行抗菌药物使用调查,包括抗菌药物种类、使用频率、科室等。结果 1 161例住院患者中,抗菌药物使用率为26.10%,其中单用率为79.54%,二联使用率为16.50%,三联及以上使用率为3.96%;在全院各科室中,使用率最高的是呼吸科,为75.61%,其次为感染科和中西医结合科,分别为67.74%、64.71%。全院治疗性用药病原学送检率为53.31%;预防用药率为18.15%;用药频率（DDDs）居前三位的依次为头孢菌素类、β-内酰胺类/β-内酰胺酶抑剂复合制剂和喹诺酮类。结论天津市第一中心医院住院患者抗菌药物应用基本合理,但个别科室使用率偏高,需要进一步加强抗菌药物合理应用的管理。Objective To carry out the cross-sectional survey on the utilization of antibiotics in Tianjin First Center Hospital.Methods In cross-sectional study,the clinical utilization of antibiotics for all inpatients from 0 to 24 h in Aug.1st,2012 was surveyed,including the kinds of antibiotics,utilization rate,and departments.Results Among 1 161 inpatients,the cross-sectional utilization rate of antibiotics was 26.10%,of which single-drug was 79.54%,two-drug 16.50%,and three-drug and above 3.96%.Among all departments in the hospital,the Department of Respiratory Medicine had the highest utilization rate,accounting for 75.61%,followed by Departments of the Communicable Disease and Combination of Traditional Chinese and Western Medicine,being 67.74% and 64.71%,respectively.Delivery rate of etiological specimens for therapeutic medication in the whole hospital was 53.31%.The prophylactic application rate was 18.15%.The top three antibiotics in the list of defined daily dose（DDD） were Cephalosporins,β-lactam/β-lactamase inhibitors,and quinolones.Conclusion In Tianjin First Central Hospital,the cross-sectional utilization rate of antibiotics is basically reasonable,but there is higher DDD in some departments.Monitoring system and methods should be further improved.

关 键 词：抗菌药物 横断面调查 合理用药 

分 类 号：R978.1[医药卫生—药品]