灯盏生脉胶囊治疗糖尿病足临床观察  

Effects of Dengzhanshengmai Capsule for Treatment of Diabetic Foot

作　　者：王国彧[1] 董彦宏[1] 崔静茹[1] 刘凯[1] 崔凯[1] 

机构地区：[1]哈尔滨医科大学附属第四医院药学部,黑龙江哈尔滨150001

出　　处：《现代生物医学进展》2013年第25期4913-4916,共4页Progress in Modern Biomedicine

基　　金：哈尔滨市科技创新人才研究专项基金(2013RFQYJ156)

摘　　要：目的:探讨灯盏生脉胶囊治疗糖尿病足患者的临床效果。方法:选取76例糖尿病足患者,随机分为照组和试验组,各38例,对照组给予基础治疗与局部治疗,试验组在对照组基础上采用灯盏生脉胶囊口服治疗(每次0.36,3次/d),共30天。比较两组患者的治疗效果、下肢血管彩超评分,以及治疗前后的溃疡面积、腓神经运动神经传导速度(MNCV)、感觉神经传导速度(SNCV)和2型糖尿病生活质量评分(DMQLS)的改变。结果:试验组治疗的总有效率明显高于对照组(P<0.05),下肢血管彩超评分疗效优于对照组(P<0.05);溃疡面积、MNCV、SNCV的改善优于对照组(P<0.05);DMQLS评分升高,与对照组比较,差异显著(P<0.05)。结论:灯盏生脉胶囊治疗糖尿病足疗效确切,并能提高患者生活质量。Objective： To investigate the clinical effect of Dengzhanshengmai capsule on patients of diabetic foot. Methods： 76 cases were randomly divided into control and experimental groups, with 38 cases in each group. Patients in control group were just given basic treatment and wound excision for diabetic foot, while patients in experimental group were based on the use of Dengzhanshengmai capsule for therapy of 30d （Each take 0.36/day）. The clinical efficiency was evaluated, and the scores of color Doppler ultrasonoscopy for lower limb blood vessele were examined. The changes of ulceration area of diabetic foot, motor nerve conduction velocity（MNCV）, sen- sory nerve conduction velocity （SNCV）, quality of life scale for patients with type 2 diabetes meUitus （DMQLS） were compared in both groups. Results： After therapy in experimental group, the clinical efficiency and effect on the scores of color Doppler ultrasonoscopy of lower limb blood vessels were superior to those in the control group（P〈0.05）. The patients in experimental group also had better effect on the minification of ulcer area and on the improment ofMNCV, SNCV and DMQOL （P〈0.05）. Coneluaion： Dengzhanshengmai capsule has effect on the patients of diabetic foot, which elevate the patient＇s qulity of life.

关 键 词：灯盏生脉胶囊 糖尿病足 生活质量 溃疡 

分 类 号：R969.4[医药卫生—药理学]