颈椎椎间隙测量及同种异体骨颈椎融合骨垫的研制  

Measure of Chinese people cervical vertebral interspaces and the design of allograft bone cervical fusion spacer

作　　者：余黎[1] 余国荣[1] 张旗 王勤志[1] 

机构地区：[1]武汉大学中南医院骨科,武汉430071 [2]湖北联结生物材料有限公司,武汉430100

出　　处：《中国临床解剖学杂志》2013年第5期511-513,517,共4页Chinese Journal of Clinical Anatomy

基　　金：武汉市科技攻关项目(201161038344-05)

摘　　要：目的根据MRI测量正常国人颈椎椎间隙数据,研制符合国人解剖学特征的同种异体骨颈椎椎间融合骨垫。方法通过MRI测量100例C2,3至C6,7每个椎间隙的前缘、中点、后缘高度值及横径宽度值、矢状径长度值,其中男性有50人(20~55岁,平均年龄38.7岁),女性有50人(20~55岁,平均年龄36.1岁)。并根据该数据设计同种异体骨颈椎椎间融合骨垫。结果同节段颈椎椎间隙正中矢状面后缘高度<前缘高度<中间高度(P<0.05),椎间隙横径大于矢状径(P<0.05),同节段同部位的测量值,男性组大于女性组(P<0.05);同种异体骨颈椎椎间融合骨垫设计为前缘高度为6.0、7.0、8.0、9.0 mm 4个型号的楔状,其表面具有倒齿结构,中央有脱钙骨基质(DBM)置入孔,用于置入DBM粉末。结论依据MRI测量的颈椎椎间隙数据设计的同种异体骨颈椎融合骨垫符合国人解剖学要求。Objoetive Based on the M IRI measure values of cervical vertebral interspace of healthy Chinese people, we aim to design the cervical allograft bone spacer in anterior cervical fusion to match the anatomical characteristics of Chinese people. M^aoda One hundred young normal Chinese people （50 males, aged 20-55 years,with an average of 38.7 years; 50 females, aged 20-55 years,with an average 36.1 years） were scanned by MRI according to gender. Measurements of the transverse diameter and sagittal diameter, as well as the anterior edge height, midpoint height and posterior edge height, were surveyed with C2,3NC6,7 vertebral interspaces. According to the data, we designed the allograft bone cervical fusion spacer. Results Located in the midline sagittal, the posterior edge height of cervical intervertebral space at the same segment was shorter than the leading edge height, which was further shorter than midpoint height （P〈0.05）. The transverse diameter of cervical intervertebral space was greater than the sagittal diameter （P〈0.05）. The male＇s measure values of the same segment was greater than the female＇s （P〈0.05）. The cervical allograft bone spacer was designed wedge-shaped and had 6,7,8,9 mm four models according to its anterior edge height. There had inverted tooth structure on the surface. The demineralized bone matrix （DBM） placed hole, which was filled with the power of DBM, was located in the center of spacer. Conclusion The cervical allograft bone spacer which was designed with the MIRI measure values of cervical vertebral interspace was compliant with the anatomy data of Chinese people.

关 键 词：颈椎椎间隙 解剖 同种异体骨 骨垫 脱钙骨基质 

分 类 号：R322.33[医药卫生—人体解剖和组织胚胎学] R681.5[医药卫生—基础医学]