脂肪来源干细胞辅助自体脂肪移植在乳房修复重建中的研究进展  

ADVANCEMENT OF ADIPOSE-DERIVED STEM CELLS ASSISTED AUTOLOGOUS LIPOTRANSFER IN BREAST REPAIR AND RECONSTRUCTION

作　　者：田春祥[1] 吕青[1] 

机构地区：[1]四川大学华西医院甲状腺乳腺外科,成都610041

出　　处：《中国修复重建外科杂志》2013年第10期1252-1255,共4页Chinese Journal of Reparative and Reconstructive Surgery

摘　　要：目的总结脂肪来源干细胞(adipose-derived stem cells,ADSCs)的主要生物学特点及ADSCs辅助自体脂肪移植在乳房修复重建中的临床应用。方法查阅近年有关ADSCs辅助自体脂肪移植的文献,并进行综述。结果 ADSCs具有多向分化潜能,能促进血管生成,且具有免疫调节能力;ADSCs辅助自体脂肪移植修复重建乳房,患者对疗效基本满意,且并发症较少,但长期安全性仍需进一步研究。结论 ADSCs辅助自体脂肪移植进行乳房修复重建具有较好的临床效果,但长期安全性需更多临床试验来证实。ObjectiveTo review the latest progress in the major biological properties of adipose-derived stem cells （ADSCs） and ADSCs assisted autologous lipotransfer in breast repair and reconstruction. MethodsRecent literature about ADSCs assisted autologous lipotransfer in breast repair and reconstruction was reviewed. ResultsADSCs have multipotential differentiation capacity, and they could promote angiogenesis and regulate immune reactions. ADSCs assisted autologous lipotransfer can obtain satisfactory effectiveness in breast repair and reconstruction with few complications, but more studies are needed to confirm the long-term safety. ConclusionADSCs assisted autologous lipotransfer has good effectiveness in breast repaired and reconstruction. But further clinical trials are needed to confirm the long-term safety.

关 键 词：脂肪来源干细胞 自体脂肪移植 乳房修复重建 

分 类 号：R622[医药卫生—整形外科]