Tubercular arthritis of the elbow joint following olecranon fracture fixation and the role of TGF-beta in its pathogenesis  

作　　者：Masood Habib Yashwant Singh Tanwar Atin Jaiswal Rajender Kumar Arya 

机构地区：[1]Department of Orthopedic Surgery, PGIMER & Dr R.M.L Hospital, New Delhi, India 11001

出　　处：《Chinese Journal of Traumatology》2013年第5期288-291,共4页中华创伤杂志（英文版）

摘　　要：Tuberculosis （TB） occurring after a closed bone fracture in the patient with no history of TB and no evidence of TB infection at the time of initial fracture is a rare entity. We report one such case of a 48-year-old female, who presented in the emergency department with an olecranon fracture which was open reduced and inter- nally fixed with tension band wiring. Patient presented in the outpatient department with serosanguineous discharge at 3 weeks after surgery. The discharge was sent for culture and sensitivity tests, and the patient was managed by anti- biotics and daily dressings. There was wound dehiscence and the underlying implant was exposed, which was removed at 12 weeks after surgery. Repeat debridements and dressings continued for 6 months, but the discharge from the wound site continued. X-rays of the elbow performed at 6 months raised the suspicion of TB, which was confirmed by Ziel-Neelsen staining and histopathological examination of the debrided tissue. Following the confirmation, patient was put on antitubercular drugs. The patient responded to anti- tubercular drug therapy （ATT）, the purulent discharge from the wound ceased, and eventually the wound healed after 2 months of starting ATT.

关 键 词：Olecranon process Fracture fixation Tuberculosis  osteoarticular Transforming growth factor beta 

分 类 号：S858.23[农业科学—临床兽医学] Q66[农业科学—兽医学]